Torrance, CANCT04375657Now EnrollingIRB Ready

Epigenetic Aging Clinical Trial in Torrance, CA

Access cutting-edge epigenetic aging treatment through this phase 2 clinical trial at a research site in Torrance. Study-provided care at no cost to qualified participants.

Sponsored by Intervene Immune, Inc.

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Expert Care in Torrance

Access epigenetic aging specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related epigenetic aging treatment provided free

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Check if you qualify for this epigenetic aging clinical trial in Torrance, CA

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Why Participate?

  • No-Cost Study Care

  • Local to Torrance

    Convenient for CA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Torrance site if eligible
  4. 4Begin participation

About This Epigenetic Aging Study in Torrance

The TRIIM-X trial is an expanded pilot clinical study that will evaluate a personalized combination treatment regimen for thymus regeneration. The thymus is a part of the immune system that declines markedly with age, and regenerating it may prevent or reverse key aspects of immunosenescence (immune system aging) and potentially prevent or reverse key parts of the aging process more generally. The study will evaluate biomarkers for epigenetic aging and immunosenescence, as well as evaluate established clinical measures and risk factors for prevention of physical frailty, cancer, cardiovascular disease, diabetes, dementia, and also infectious diseases, including flu and COVID-19. The study uses multiple agents in combination with personalized doses of recombinant human growth hormone (somatropin), metformin, and DHEA, in a similar manner to how the combination treatment was applied in the earlier TRIIM trial at Stanford, which demonstrated strong statistical significance for the primary efficacy endpoints that will be evaluated in TRIIM-X. Somatropin is approved by the FDA for adult growth hormone deficiency and its use in the study is guided by prior safety data established for that use and also based on safety data available on its prior use in the TRIIM trial and in clinical practice in healthy elderly individuals. There will also be control groups that enable testing of biomarker variability and the contribution of individual medications within the combination treatment. The objective of the study is to obtain information needed for designing an effective personalized and adaptive treatment regimen for a larger and more diverse study population, and to obtain additional proof of principle for the new use of the medications and biomarkers for preventive medicine. The duration of treatment in the TRIIM-X trial will be 12 months.

Sponsor: Intervene Immune, Inc.

Who Can Participate

Inclusion Criteria

Male or female volunteers
Aged 40 to 80 years, inclusive
All ethnicities
Able to participate in 12-month study
Able to provide informed consent

Exclusion Criteria

Malignancies or high risk of malignancy, as suggested by familial risk or personal medical history
Premenopausal women
Postmenopausal women on HRT
IGF-1 levels \< 90 ng/ml or \>300 ng/ml
Diagnosed or suspected growth hormone resistance
Known growth hormone deficiency based on stimulation testing
Pre-existing carpal tunnel syndrome
Significant arthritis/arthralgia/joint swelling
Bradycardia (\<55 bpm), significant hypertension (systolic \>160 mmHg, or diastolic \>90 mmHg) despite treatment, serious angina, or other serious cardiovascular disease or cardiovascular disease risk factors
Excessive skin growths (e.g., flat warts) without cryosurgical options
BMI of 35 or greater
PSA level above the age-adjusted normal range for reasons other than confirmed prostatitis
Testosterone levels above the upper limit of normal
Levels of C-reactive protein (CRP) above the upper limit of normal
Type 1 or pre-existing Type 2 diabetes
Uncorrected hypothyroidism
HIV infection
Allergy or other sensitivity to study medications
Other unstable medical conditions
Use of GH within the last 5 years
Participation in a clinical research trial within 30 days prior to enrollment
Use of chronic glucocorticoid therapy
Unwilling to discontinue androgen supplementation if testosterone levels are above the upper limit of normal
Ongoing treatment with carbonic anhydrase inhibitors
Ketogenic diet, calorie-restricted diet, or prolonged fasting, without willingness to discontinue these diets or adhere to an alternative diet during the study
Alcoholism or drug addiction
Smoking or unwillingness to quit smoking
Cognitive impairment, illiteracy, inability or unwillingness to give voluntary informed consent

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Torrance?

Yes, this clinical trial (NCT04375657) has an active research site in Torrance, CA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Epigenetic Aging Treatment Options in Torrance, CA

If you're searching for epigenetic aging treatment options in Torrance, CA, this clinical trial (NCT04375657) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Torrance research site is actively enrolling participants for this phase 2 clinical trial. You'll receive care from experienced epigenetic aging specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all epigenetic aging clinical trials near you to find additional studies recruiting in your area.

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