NCT05950438 · Northwestern University
Investigating Outcomes of Elective Robotic Transhiatal Esophagectomy
What this study is about
The primary goal of this study is to collect short-term and long-term health outcomes of a robotic transhiatal esophagectomy procedure. Clinical (or health) outcomes measure the effect of the procedure on your overall health status. During this procedure, the surgeon will remove all or part of your esophagus. We want to identify patients who will have this procedure.
View original scientific description
The primary goal of this study is to collect short-term and long-term health outcomes of a robotic transhiatal esophagectomy procedure. Clinical (or health) outcomes measure the effect of the procedure on your overall health status. During this procedure, the surgeon will remove all or part of your esophagus. We want to identify patients who will have this procedure. We will look at data elements before, during, and after your procedure to understand the impact of this surgery on your post-operative clinical outcomes.
Interventions
PROCEDURE
Esophagectomy
Esophagectomy is a complex surgical procedure performed to treat various esophageal disorders. The surgery involves the removal of all or part of the esophagus and reconstruction using other parts of the gastrointestinal tract.
Primary outcome measures
Number of Participants with Anastomotic Leak
Time frame: During first 3 months postop
Postoperative Complication
Number of Participants with Esophageal Stricture
Time frame: During first 3 months postop
Postoperative Complication
Number of Participants with Pneumonia
Time frame: During first 3 months postop
Postoperative Complication
Number of Participants Requiring Ventilation >48 Hours
Time frame: During first 3 months postop
Postoperative Complication
Number of Participants with Empyema
Time frame: During first 3 months postop
Postoperative Complication
Number of Participants with Pulmonary Embolism
Time frame: During first 3 months postop
Postoperative Complication
Number of Participants with Deep Venous Thrombosis
Time frame: During first 3 months postop
Postoperative Complication
Number of Participants with Gastric Outlet Obstruction
Time frame: During first 3 months postop
Postoperative Complication
Number of Participants with Stroke
Time frame: During first 3 months postop
Postoperative Complication
Number of Participants with Atrial Fibrillation
Time frame: During first 3 months postop
Postoperative Complication
Number of Participants with Vocal Cord Paralysis
Time frame: During first 3 months postop
Postoperative Complication
Number of Participants with Myocardial Infarction
Time frame: During first 3 months postop
Postoperative Complication
Number of Participants with Chylothorax
Time frame: During first 3 months postop
Postoperative Complication
Number of Participants with Acute Renal Injury
Time frame: During first 3 months postop
Postoperative Complication
Number of Participants with Wound Infections
Time frame: During first 3 months postop
Postoperative Complication
Rates of Re-operation
Time frame: During first 3 months postop
Postoperative Complication
Rates of Re-Admission
Time frame: During first 3 months postop
Postoperative Complication
Number of Participants with Intensive Care Unit (ICU) Stay
Time frame: During first 3 months postop
Postoperative Complication
Rates of Length of Hospital Stay
Time frame: Postoperative
Postoperative Complication
Rates of 30-day Survival
Time frame: Postoperative
Postoperative Complication
Rates of 90-day Survival Rates
Time frame: Postoperative
Postoperative Complication
Who can participate
This study lists these criteria on ClinicalTrials.gov. A study coordinator reviews eligibility during screening — this page does not determine whether you qualify.
Inclusion criteria
- Adult patients (18 years or older)
- Patients undergoing elective esophagectomy for any indication
- Patients who have already had an elective esophagectomy for any indication
- Patients with consent providing capacity
Exclusion criteria
- Patients undergoing emergent esophagectomy
- Adults unable to consent
- Individuals who are not yet adults (infants, children, teenagers)
- Pregnant women
- Vulnerable Populations
Where
- Chicago, Illinois
Related conditions & keywords
Frequently asked questions
What is a clinical trial?
A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.
Is it safe to participate?
Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.
Will I be compensated?
Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.
Will I receive a placebo instead of treatment?
When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.
Can I leave a trial if I change my mind?
Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.
How long does a clinical trial last?
Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.
Data: ClinicalTrials.gov · synced May 26, 2026 · Source of record for eligibility and locations