Memphis, TNNCT07428447Now EnrollingIRB Ready

Essential Tremor, Movement Disorders Clinical Trial in Memphis, TN

Access cutting-edge essential tremor, movement disorders treatment through this clinical trial at a research site in Memphis. Study-provided care at no cost to qualified participants.

Sponsored by CND Life Sciences

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Expert Care in Memphis

Access essential tremor, movement disorders specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related essential tremor, movement disorders treatment provided free

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Check if you qualify for this essential tremor, movement disorders clinical trial in Memphis, TN

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Why Participate?

  • No-Cost Study Care

  • Local to Memphis

    Convenient for TN residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Memphis site if eligible
  4. 4Begin participation

About This Essential Tremor, Movement Disorders Study in Memphis

Background and Rationale Essential tremor (ET) affects over 6 million Americans and approximately 5% of adults over age 60. Patients with ET have a 10-20 times higher risk of developing Parkinson's disease (PD) compared to age-matched populations, with approximately 1% converting to PD annually. Post-mortem studies reveal Lewy body pathology in some ET patients, suggesting a subset may have prodromal PD. Current diagnostic tools (DaTscan, SYNTap) are either insufficiently sensitive for early disease, too expensive, or too invasive for routine screening. The Syn-One Test offers a minimally invasive approach to detect phosphorylated α-synuclein (P-SYN) pathology in skin biopsies. Primary Objectives 1. Identify which ET patients have P-SYN pathology indicative of prodromal PD 2. Predict which patients are most likely to phenoconvert to PD

Sponsor: CND Life Sciences

Who Can Participate

Inclusion Criteria

Age 50-85 years old
Diagnosis of ET as defined by the 2018 MDS Task force paper "1) isolated tremor syndrome of bilateral upper limb action tremor 2) at least 3 years' duration 3) with or without tremor in other locations (e.g., head, voice, or lower limbs) 4) absence of other neurological signs, such as dystonia, ataxia, or parkinsonism." OR
Diagnosis of ET-Plus as stated by the 2018 MDS Task force paper, "Tremor with the characteristics of ET and additional neurological signs of uncertain significance such as impaired tandem gait, questionable dystonic posturing, memory impairment, or other mild neurologic signs of unknown significance that do not suffice to make an additional syndrome classification or diagnosis. ET with tremor at rest should be classified here."
Willing to participate in all study procedures
Able and willing to provide written informed consent

Exclusion Criteria

Under age 50, Over age 85
Clinical evidence of severe peripheral vascular disease
Clinically active coronary artery or cerebrovascular disease
Participant is currently on anticoagulant or dual anti-platelet therapy
Allergic reaction to local anesthesia
History of or increased risk for impaired wound healing, scarring, or keloid formation
Diagnosis of ET or ET-Plus that is clinically determined to likely be secondary to brain injury or vascular compromise
History of other neurodegenerative disorder or evidence of neurological co-pathology
Abnormal DaTscan
Participant is currently receiving treatment with carbidopa-levodopa for PD
Isolated focal tremors (head, voice)
Task-specific tremor (e.g., primary writing tremor)
Position-specific tremors that does not otherwise meet clinical diagnostic criteria for ET
Sudden onset and step-wise deterioration

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Memphis?

Yes, this clinical trial (NCT07428447) has an active research site in Memphis, TN that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Essential Tremor, Movement Disorders Treatment Options in Memphis, TN

If you're searching for essential tremor, movement disorders treatment options in Memphis, TN, this clinical trial (NCT07428447) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Memphis research site is actively enrolling participants for this clinical trial. You'll receive care from experienced essential tremor, movement disorders specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all essential tremor, movement disorders clinical trials near you to find additional studies recruiting in your area.

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