Chapel Hill, NCNCT06331052Now EnrollingIRB Ready

Essential Tremor Clinical Trial in Chapel Hill, NC

Access cutting-edge essential tremor treatment through this clinical trial at a research site in Chapel Hill. Study-provided care at no cost to qualified participants.

Sponsored by University of North Carolina, Chapel Hill

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Expert Care in Chapel Hill

Access essential tremor specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related essential tremor treatment provided free

Apply for This Chapel Hill Location

Check if you qualify for this essential tremor clinical trial in Chapel Hill, NC

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Chapel Hill

    Convenient for NC residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Chapel Hill site if eligible
  4. 4Begin participation

About This Essential Tremor Study in Chapel Hill

The investigators propose to advance Vim-FUSA (Ventral Intermediate Nucleus - Focused Ultrasound Ablation) with the support of 3-D tractography, a neuroimaging technique to visually represent nerve tracts within the brain. The investigators hypothesize that 3-D tractography Vim-FUSA will improve the Vim ablation compared to standard Vim-FUSA and prove safe and feasible in the clinical setting. The investigators also hypothesize that intraoperative magnetic resonance (i-MR) monitoring will differentiate ablated tissue from immediate perilesional edema and accurately predict the Vim-FUSA clinical outcomes.

Sponsor: University of North Carolina, Chapel Hill

Who Can Participate

Inclusion Criteria

Diagnosis of moderate to severe ET agreed upon by at least two movement disorder trained physicians
Symptoms refractory to at least two medications
Stable medication regimen for at least 4 weeks prior to screening
Willing and able to participate in all follow-up visits
Willing and able to undergo MR imaging.

Exclusion Criteria

Uncontrolled hypertension
Medically unstable coronary artery disease
Coagulopathy, anticoagulant therapy, or inability to temporarily stop any antithrombotic medication
Tremor disorders other than ET
Unwilling or unable to undergo tremor surgery while awake
Significant and non-correctible motion artifact in imaging
Pregnant at the time of enrollment or preoperative evaluation
History of psychosis
History of drug or alcohol abuse
Prior brain surgery such as Vim-FUSA, deep brain stimulation, and gamma knife thalamotomy
Botulinum toxin injection in the tremor-impacted areas three months prior to the baseline assessment and until 3-months after Vim-FUSA
Skull density ratio lower than 0.4
Does not qualify for FDA-approved clinical use based on current FDA labeling
Any significant issue raised by the neurologist or neurosurgeon that may compromise participant safety or potentially interfere with study interpretation.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Chapel Hill?

Yes, this clinical trial (NCT06331052) has an active research site in Chapel Hill, NC that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Essential Tremor Treatment Options in Chapel Hill, NC

If you're searching for essential tremor treatment options in Chapel Hill, NC, this clinical trial (NCT06331052) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Chapel Hill research site is actively enrolling participants for this clinical trial. You'll receive care from experienced essential tremor specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all essential tremor clinical trials near you to find additional studies recruiting in your area.

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