NCT07436078 · Barbara Ann Karmanos Cancer Institute
Culturally Adapting an Intervention to Increase Genetic Testing in African American Cancer Survivors
What this study is about
The goal of this clinical trial is to culturally adapt an educational genetic counseling intervention to increase the uptake in genetic counseling and testing among African Americans at risk for heredity cancers.
View original scientific description
The goal of this clinical trial is to culturally adapt an educational genetic counseling intervention to increase the uptake in genetic counseling and testing among African Americans at risk for heredity cancers. With the help of community stakeholders and clinical genetic professionals the investigators will: * adapt and refine a culturally relevant online educational genetic counseling program for at-risk African Americans * Test the effects of the educational program * collaborate with community leaders and clinical genetic professionals to translate study findings, develop a road map for dissemination to the community, and identify barriers to prepare for future trials. Participants from Detroit Research on Cancer Survivor group will be offered enrollment.
Who can participate
This study lists these criteria on ClinicalTrials.gov. A study coordinator reviews eligibility during screening — this page does not determine whether you qualify.
Inclusion criteria
- Participants enrolled in Detroit Research on Cancer Survivors (Detroit ROCS)
- Diagnosis of Primary Breast, prostate, or colorectal cancer on or after 1/1/2013
- have received or currently receiving care at Karmanos Cancer Institute
- meet one or more of the National Comprehensive Cancer Network (NCCN) guidelines for cancer genetic testing as described below Female breast
- personal diagnosis at age ≤50
- personal history of the triple-negative subtype
- at least 1 close (first- or second-degree) relative diagnosed with breast cancer at age \<50
- at least 1 close relative diagnosed with ovarian cancer
- 2+ close relatives diagnosed with breast or prostate cancer
- age \<50 AND another primary breast cancer at any age
- 2+ primary breast cancers at any age OR Prostate
- personal history of high-risk or very high-risk prostate cancer
- personal history of regional or metastatic prostate cancer
- personal history of less than high-risk prostate cancer with a suggestive family history (i.e., father or brother or multiple relatives with prostate cancer diagnosed at age \<60; at least 1 relative with breast, ovarian, or pancreatic cancer; or at least 1 relative with colorectal, ovarian, pancreatic, or kidney cancer) OR Colorectal
- personal diagnosis at age ≤50
- at least 1 close relative diagnosed with HNPCC at age \<50
- at least 2 close relatives diagnosed with an HNPCC cancer at any age
- colorectal and \>=1 primary endometrial, ovarian, gastric, pancreatic, or prostate
Exclusion criteria
- Previous genetic counseling and/or testing
Where
- Detroit, Michigan
Frequently asked questions
What is a clinical trial?
A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.
Is it safe to participate?
Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.
Will I be compensated?
Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.
Will I receive a placebo instead of treatment?
When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.
Can I leave a trial if I change my mind?
Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.
How long does a clinical trial last?
Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.
Data: ClinicalTrials.gov · synced Jun 23, 2026 · Source of record for eligibility and locations