Roanoke, VANCT06861309Now EnrollingIRB Ready

Fetal Growth Restriction (FGR) Clinical Trial in Roanoke, VA

Access cutting-edge fetal growth restriction (fgr) treatment through this clinical trial at a research site in Roanoke. Study-provided care at no cost to qualified participants.

Sponsored by Carilion Clinic

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Expert Care in Roanoke

Access fetal growth restriction (fgr) specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related fetal growth restriction (fgr) treatment provided free

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Check if you qualify for this fetal growth restriction (fgr) clinical trial in Roanoke, VA

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Why Participate?

  • No-Cost Study Care

  • Local to Roanoke

    Convenient for VA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Roanoke site if eligible
  4. 4Begin participation

About This Fetal Growth Restriction (FGR) Study in Roanoke

The goal of this proof-of-concept, case-control, clinical trial is to evaluate the efficacy of using two newer ultrasound technologies, quantitative ultrasound (QUS) and ultrafast power Doppler imaging (uPDI), to evaluate the health of the placenta, visualize blood flow through the placental vasculature by color Doppler imaging in singleton pregnancies with and without fetal growth restriction (FGR). * Our primary objective is to investigate the ability of using these ultrasound technologies to distinguish healthy pregnancies from those affected by FGR, a condition characterized by a fetal weight below the 10th percentile for the gestational age or abdominal circumference of the pregnancy. * Secondary aims include longitudinal evaluation of differences in QUS and uPDI imaging over gestation and changes in these measures with evolution of utero-placental insufficiency including with the development of abnormal umbilical-artery Doppler testing, diagnosis of severe FGR, identification of stillbirth, and detection of preeclampsia or preterm birth. Investigators will compare QUS/uPDI imaging and values in pregnancies determined to be healthy by approved, standard-of-care growth ultrasounds to those diagnosed with FGR. Participants will receive research ultrasounds with the experimental Verasonics Vantage 256 system (Verasonics, Inc, Kirkland, WA) utilizing uPDI/QUS every three weeks following their routine growth ultrasound evaluation until delivery. Demographic, obstetric, and delivery-related information, as well as portions of subjects' past medical history will be utilized by researchers to further contextualize imaging and variables gathered during the research ultrasounds.

Sponsor: Carilion Clinic

Who Can Participate

Inclusion Criteria

Normal-Fetal-Weight Pregnancies Arm: Patient at least 18 to 45 years of age at screening
Normal-Fetal-Weight Pregnancies Arm: Non-anomalous, singleton gestation without suspected genetic disorders or growth abnormalities
Normal-Fetal-Weight Pregnancies Arm: Low-risk aneuploidy screening, if performed
Normal-Fetal-Weight Pregnancies Arm: Intention to deliver at Carilion Roanoke Memorial Hospital (CRMH) or Carilion New River Valley Medical Center (CNRVMC)
Normal-Fetal-Weight Pregnancies Arm: Anatomical survey has been performed
Normal-Fetal-Weight Pregnancies Arm: Pregnancy without current fetal growth restriction (FGR) diagnosis
Normal-Fetal-Weight Pregnancies Arm: Subject willing and able to provide informed consent Note: Verify that the most recent version of the ICF was used to consent the subject
Fetal-Growth-Restricted (FGR) Pregnancies Arm: Patient at least 18 to 45 years of age at screening
Fetal-Growth-Restricted (FGR) Pregnancies Arm: Non-anomalous, singleton gestation without suspected genetic disorders
Fetal-Growth-Restricted (FGR) Pregnancies Arm: Low-risk aneuploidy screening, if performed
Fetal-Growth-Restricted (FGR) Pregnancies Arm: Intention to deliver at Carilion Roanoke Memorial Hospital (CRMH) or Carilion New River Valley Medical Center (CNRVMC)
Fetal-Growth-Restricted (FGR) Pregnancies Arm: Anatomical survey has been performed
Fetal-Growth-Restricted (FGR) Pregnancies Arm: Pregnancy diagnosed with fetal growth restriction (FGR) by estimated fetal weight \<10th centile or abdominal circumference measurements \<10th centile
Fetal-Growth-Restricted (FGR) Pregnancies Arm: Subject willing and able to provide informed consent Note: Verify that the most recent version of the ICF was used to consent the subject

Exclusion Criteria

Normal-Fetal-Weight Pregnancies Arm: Multiple gestations
Normal-Fetal-Weight Pregnancies Arm: Known fetal anomaly affecting biometric measurements
Normal-Fetal-Weight Pregnancies Arm: Suspected fetal genetic disorder(s)
Normal-Fetal-Weight Pregnancies Arm: Suspected fetal infection(s)
Normal-Fetal-Weight Pregnancies Arm: Non-English or Spanish-speaking
Normal-Fetal-Weight Pregnancies Arm: Unstable housing or transportation
Normal-Fetal-Weight Pregnancies Arm: Any other criterion which, in the clinical judgement of the investigator, would make the subject unsuitable for study enrollment.
Fetal-Growth-Restricted (FGR) Pregnancies Arm: Multiple gestations
Fetal-Growth-Restricted (FGR) Pregnancies Arm: Known fetal anomaly affecting biometric measurements
Fetal-Growth-Restricted (FGR) Pregnancies Arm: Suspected fetal genetic disorder(s)
Fetal-Growth-Restricted (FGR) Pregnancies Arm: Suspected fetal infection(s)
Fetal-Growth-Restricted (FGR) Pregnancies Arm: Non-English or Spanish-speaking
Fetal-Growth-Restricted (FGR) Pregnancies Arm: Unstable housing or transportation
Fetal-Growth-Restricted (FGR) Pregnancies Arm: Any other criterion which, in the clinical judgement of the investigator, would make the subject unsuitable for study enrollment.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Roanoke?

Yes, this clinical trial (NCT06861309) has an active research site in Roanoke, VA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Fetal Growth Restriction (FGR) Treatment Options in Roanoke, VA

If you're searching for fetal growth restriction (fgr) treatment options in Roanoke, VA, this clinical trial (NCT06861309) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Roanoke research site is actively enrolling participants for this clinical trial. You'll receive care from experienced fetal growth restriction (fgr) specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all fetal growth restriction (fgr) clinical trials near you to find additional studies recruiting in your area.

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