Wilmington, DENCT07552766Now EnrollingIRB Ready

Fracture Arm Clinical Trial in Wilmington, DE

Access cutting-edge fracture arm treatment through this phase 4 clinical trial at a research site in Wilmington. Study-provided care at no cost to qualified participants.

Sponsored by Nemours Children's Clinic

Quick Self-Assessment

See if you qualify for this Wilmington location

Preparing your pre-screening questions…

Expert Care in Wilmington

Access fracture arm specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related fracture arm treatment provided free

Apply for This Wilmington Location

Check if you qualify for this fracture arm clinical trial in Wilmington, DE

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Wilmington

    Convenient for DE residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Wilmington site if eligible
  4. 4Begin participation

About This Fracture Arm Study in Wilmington

This study is a prospective, randomized, double-blind clinical trial evaluating whether intraoperative intravenous lidocaine infusion (IVLI) reduces opioid requirements and improves postoperative pain control in children undergoing surgical fixation of upper extremity long bone fractures under general anesthesia. Ninety pediatric patients, ages 3-18 will be enrolled and randomized 1:1 to receive either IV lidocaine or placebo (normal saline) during surgery. All participants will receive standardized anesthesia care and postoperative pain management. Opioid consumption and pain scores will be measured intraoperatively and throughout the postoperative recovery, with the primary outcome focused on total opioid use 60 minutes after arrival to the post-anesthesia care unit (PACU). Secondary outcomes include opioid use at additional time points, postoperative pain scores, PACU length of stay, rescue antiemetic use and the relationship between infusion duration and outcomes. Patients will be closely monitored for signs of local anesthetic systemic toxicity and other adverse events. The goal of this study is to determine whether IV lidocaine is an effective opioid-sparing adjunct in pediatric orthopedic surgery and to support safer, multimodal analgesia strategies.

Sponsor: Nemours Children's Clinic

Who Can Participate

Inclusion Criteria

Patients aged 3-18 years
Patients \> 10 kg
Patients who present to Nemours Children's Hospital - Delaware Valley (NCH-DE) for surgical fixation of upper extremity fractures from distal humerus to distal radius

Exclusion Criteria

Children \< 3 years or \> 18 years
Patients with allergy to local anesthetics
Patients who are eligible for an receive a peripheral nerve block
Patients with multi-trauma or open fractures
Patients with previous history of seizure disorder
Patients with conduction abnormalities or cardiac arrhythmia requiring chronic treatment
Patients on strong CYP450 inhibitors (fluvoxamine, erythromycin, ciprofloxacin, rifampin, allopurinol, ketoconazole, itraconazole)
Patients with chronic kidney or liver dysfunction
Patients with planned use of continuous infusion pain medications (opioids, ketamine, alpha-2- agonists)
Patients with positive pregnancy test prior to surgery or nursing mothers
Patients who parents decline enrollment

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Wilmington?

Yes, this clinical trial (NCT07552766) has an active research site in Wilmington, DE that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Fracture Arm Treatment Options in Wilmington, DE

If you're searching for fracture arm treatment options in Wilmington, DE, this clinical trial (NCT07552766) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Wilmington research site is actively enrolling participants for this phase 4 clinical trial. You'll receive care from experienced fracture arm specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all fracture arm clinical trials near you to find additional studies recruiting in your area.

More Rheumatoid Arthritis Trials in Wilmington, DE

See all rheumatoid arthritis clinical trials recruiting in Wilmington — not just this study.

Browse Rheumatoid Arthritis Trials in Wilmington →

Browse More Trials by Condition

Ready to Join in Wilmington?

Take the first step toward participating in this groundbreaking clinical trial

Secure · Expert Care · Wilmington, DE