Kansas City, MONCT02484248Now EnrollingIRB Ready

Functional Dyspepsia Clinical Trial in Kansas City, MO

Access cutting-edge functional dyspepsia treatment through this clinical trial at a research site in Kansas City. Study-provided care at no cost to qualified participants.

Sponsored by Craig A. Friesen, MD

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Expert Care in Kansas City

Access functional dyspepsia specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related functional dyspepsia treatment provided free

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Check if you qualify for this functional dyspepsia clinical trial in Kansas City, MO

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Why Participate?

  • No-Cost Study Care

  • Local to Kansas City

    Convenient for MO residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Kansas City site if eligible
  4. 4Begin participation

About This Functional Dyspepsia Study in Kansas City

Acid reduction remains the most common treatment prescribed empirically by pediatric gastroenterologists for children with functional dyspepsia (FD). When acid reduction therapy fails to provide patients with a therapeutic effect, ketotifen and cromolyn, mast cell stabilizers, represent an attractive potential therapy given data implicating mast cells in the generation of dyspeptic symptoms. Although there have been no adult or pediatric studies on the use of mast cell stabilizers in patients with FD, benefit has been demonstrated in adults with IBS and children with eosinophilic gastroenteritis. Additionally, previous studies show mucosal eosinophilia is highly correlated with functional dyspepsia. Our usual current treatment pathway for functional dyspepsia in association with duodenal mucosal eosinophilia is as follows: acid-reducing medication/montelukast β†’ addition of H1 antagonist β†’ addition of budesonide β†’ addition of oral cromolyn. If ketotifen is effective, it offers the advantage of being able to replace both the H1 antagonist and the oral cromolyn at a substantially reduced cost (approximately 10% of the cost of cromolyn alone). This study aims to introduce ketotifen earlier in the treatment pathway to examine its efficacy on children with functional dyspepsia in association with duodenal eosinophilia.

Sponsor: Craig A. Friesen, MD

Who Can Participate

Inclusion Criteria

between the ages of 8 and 17 years, inclusive
abdominal pain of at least 8 weeks duration and fulfilling symptom-based criteria for functional dyspepsia(5);
previous endoscopy with biopsies demonstrating \>20 eosinophils/high powered field on duodenal mucosal biopsies;
previous treatment with acid-reduction therapy and montelukast with a level 3 (as defined below)or lesser response;
evidence of written parental permission (consent) and subject assent;
Negative pregnancy screening for females of child bearing potential.

Exclusion Criteria

previous treatment with ketotifen;
treatment with oral corticosteroids or oral cromolyn sodium in the 6 months prior to enrollment;
any prior history of diabetes mellitus, cancer, chronic cardiac disease, respiratory disease, or renal disease requiring routine medical care;
Pregnant/planning to become pregnant;
Post-menarche females unwilling to use highly-efficacious contraception to prevent pregnancy;
Epilepsy or history of seizures;
Liver disease or elevation of liver enzymes;
Use of oral hypoglycemic medications, antipsychotics, benzodiazepines, tricyclic antidepressants, barbiturates, or opioids;
Allergy to ketotifen or other products in capsule
Refusal of Urine pregnancy test in post-menarchal females.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Kansas City?

Yes, this clinical trial (NCT02484248) has an active research site in Kansas City, MO that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Functional Dyspepsia Treatment Options in Kansas City, MO

If you're searching for functional dyspepsia treatment options in Kansas City, MO, this clinical trial (NCT02484248) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Kansas City research site is actively enrolling participants for this clinical trial. You'll receive care from experienced functional dyspepsia specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all functional dyspepsia clinical trials near you to find additional studies recruiting in your area.

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