Columbus, OHNCT07215949Now EnrollingIRB Ready

Generalized Myasthenia Gravis (gMG) Clinical Trial in Columbus, OH

Access cutting-edge generalized myasthenia gravis (gmg) treatment through this phase 3 clinical trial at a research site in Columbus. Study-provided care at no cost to qualified participants.

Sponsored by Miriam Freimer

Quick Self-Assessment

See if you qualify for this Columbus location

Preparing your pre-screening questions…

Expert Care in Columbus

Access generalized myasthenia gravis (gmg) specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related generalized myasthenia gravis (gmg) treatment provided free

Apply for This Columbus Location

Check if you qualify for this generalized myasthenia gravis (gmg) clinical trial in Columbus, OH

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Columbus

    Convenient for OH residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Columbus site if eligible
  4. 4Begin participation

About This Generalized Myasthenia Gravis (gMG) Study in Columbus

This is an open-label, multicenter, interventional phase 3b study in participants with AChR+ gMG and severe exacerbation that require hospitalization. Patients will receive subcutaneous zilucoplan injections daily for 12 weeks. Participation in the study will last for approximately 18 weeks.

Sponsor: Miriam Freimer

Who Can Participate

Inclusion Criteria

Patient determined to have severe MG exacerbation (e.g. bulbar and/or respiratory symptoms requiring hospitalization, neck extension weakness)
MGFA class II - IVb
Male or female aged ≥18
MG-ADL ≥6 in non-ocular domains
Serology - AChR antibody positive (or historically available data)
If female of child-bearing potential (i.e., not surgically sterile or post-menopausal defined as age \> 51 years without menses for ≥ 2 years), negative serum pregnancy test at screening
Women of child-bearing potential or men with sexual partners of childbearing potential must be willing to use an acceptable method of birth control for the duration of the study and for 40 days after the last dose of study drug therapy. Acceptable methods of birth control include abstinence, oral contraceptives, the contraceptive patch, intra-uterine device, the contraceptive ring, and or barrier contraception such as condoms with spermicide.
Completed or updated meningococcal vaccination or initiated meningococcal vaccination with appropriate antibiotic prophylaxis according to current USPI and ACIP guidelines

Exclusion Criteria

History of meningococcal disease
Participants requiring intubation prior to study start.
Recent significant infections which could have caused exacerbation e.g. sepsis and wound infections
Pregnancy or lactating
Recent surgery (\<4 weeks). Minor procedures/surgeries allowed at the discretion of the site principal investigator
Current use or known failure of C5 inhibitors in the previous 3 months
Initiation of plasma exchange or IVIG in the past 4 weeks
Participation in concurrent clinical trial with a therapeutic medication
Rituximab use in the previous 9 months
Any clinically significant condition or illness, which, in the opinion of the PI, would pose a risk to the subject or might confound the study

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Columbus?

Yes, this clinical trial (NCT07215949) has an active research site in Columbus, OH that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Generalized Myasthenia Gravis (gMG) Treatment Options in Columbus, OH

If you're searching for generalized myasthenia gravis (gmg) treatment options in Columbus, OH, this clinical trial (NCT07215949) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Columbus research site is actively enrolling participants for this phase 3 clinical trial. You'll receive care from experienced generalized myasthenia gravis (gmg) specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all generalized myasthenia gravis (gmg) clinical trials near you to find additional studies recruiting in your area.

More Myasthenia Gravis Trials in Columbus, OH

See all myasthenia gravis clinical trials recruiting in Columbus — not just this study.

Browse Myasthenia Gravis Trials in Columbus →

Browse More Trials by Condition

Myasthenia Gravis TrialsRheumatoid Arthritis TrialsAnkylosing Spondylitis TrialsErectile Dysfunction TrialsAll Conditions →

Ready to Join in Columbus?

Take the first step toward participating in this groundbreaking clinical trial

Secure · Expert Care · Columbus, OH