NCT07755943 · Shaklee Corporation
An Evaluation of Long-Term Supplement Use on Biological Age and Metabolic Health Markers - The BioAge Trial
What this study is about
This study will evaluate whether dietary supplement use (\> 1 year) is associated with differences in biological age relative to chronological age, as well as differences in metabolic health and functional fitness tests.
View original scientific description
This study will evaluate whether dietary supplement use (\> 1 year) is associated with differences in biological age relative to chronological age, as well as differences in metabolic health and functional fitness tests.
Interventions
OTHER
No Intervention: Observational Cohort
No intervention: observational cohort
Primary outcome measures
Difference between biological and chronological age (years) calculated using a validated biological age calculator
Time frame: Baseline single assessment for this observational study
Differences will be compared to an NHANES cohort, where possible.
Who can participate
This study lists these criteria on ClinicalTrials.gov. A study coordinator reviews eligibility during screening — this page does not determine whether you qualify.
Inclusion criteria
- Adults aged 40 years or older.
- Verified long-term Sponsor supplement use (\>1 year).
- Willing and able to provide informed consent and comply with study procedures.
- Able to fast overnight (\>8 hours) prior to the study visit.
- Willing and able to travel to the test site.
- Ambulatory and currently free of injury or other physical impairment that hinders mobility.
- Willing to use a personal smart phone or computer with internet access and active email address.
- Willing to adhere to all study procedures and sign forms providing informed consent to participate in the study and authorization to release relevant protected health information.
Exclusion criteria
- Current or recent (within 6 months) diagnosis of cancer except for non-melanoma skin cancer.
- Participant is pregnant or lactating.
- Participant has a pacemaker or other implanted electronic device.
- Any condition the study staff believes would interfere with the participant's ability to provide informed consent or comply with the study protocol, which might confound the interpretation of the study results or put the person at undue risk.
Where
- Addison, Illinois
Collaborators
Biofortis Clinical Research, Inc., Nlumn LLC
Related conditions & keywords
Frequently asked questions
What is a clinical trial?
A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.
Is it safe to participate?
Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.
Will I be compensated?
Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.
Will I receive a placebo instead of treatment?
When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.
Can I leave a trial if I change my mind?
Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.
How long does a clinical trial last?
Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.
Data: ClinicalTrials.gov · synced Aug 10, 2026 · Source of record for eligibility and locations