Research Triangle Park, NCNCT01500447Now EnrollingIRB Ready

Genetic Disorder Clinical Trial in Research Triangle Park, NC

Access cutting-edge genetic disorder treatment through this clinical trial at a research site in Research Triangle Park. Study-provided care at no cost to qualified participants.

Sponsored by National Institute of Environmental Health Sciences (NIEHS)

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Expert Care in Research Triangle Park

Access genetic disorder specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related genetic disorder treatment provided free

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Why Participate?

  • No-Cost Study Care

  • Local to Research Triangle Park

    Convenient for NC residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Research Triangle Park site if eligible
  4. 4Begin participation

About This Genetic Disorder Study in Research Triangle Park

Background: \- During puberty, children begin to develop into adults. Problems with the hormones released during puberty can affect the reproductive system. Some people have low hormone levels that severely delay or prevent puberty. Others start puberty abnormally early. Other people may have a normal puberty but develop reproductive disorders later in life. Researchers want to study people with reproductive disorders to learn more about how these disorders may be inherited. Objectives: \- To learn how reproductive system disorders may be inherited. Eligibility: * People with one of the following problems: * Abnormally early puberty * Abnormally late or no puberty * Normal puberty with hormonal problems that develop later in life * People who have not yet had puberty but have symptoms that indicate low hormone levels. Design: * Participants will provide a blood sample for testing. They will complete a questionnaire about their symptoms. They will also have a scratch-and-sniff test to study any problems with their ability to smell. * Participant medical records will be reviewed. Participants will also provide a family medical history. * Family members of those in the study may be invited to participate. * Treatment will not be provided as part of this study.

Sponsor: National Institute of Environmental Health Sciences (NIEHS)

Who Can Participate

Inclusion Criteria

The essential inclusion criteria include:
failure to go through a normal, age-appropriate, spontaneous puberty and low sex steroid levels in the setting of low/normal gonadotropins (due to substantial variability among patient presentations, this will be based on the clinical judgement of the Investigator), or
abnormally early development of puberty, or
normal puberty with subsequent development of low gonadotropin levels, or
individuals with features indicating an increased risk of hypogonadotropic hypogonadism.
Family members: both affected and unaffected family members are strongly encouraged to participate.

Exclusion Criteria

Since hypogonadotropic hypogonadism is a rare condition, this protocol remains open to enrollment so that we may study all subjects that are both qualified and interested in participating. Because HH represents a spectrum, where associated clinical findings may provide phenotypic clues to the assessment of inheritability and underlying physiology, exclusion criteria are very limited:
Patients who have additional pituitary deficiencies, effectively ruling out isolated GnRH deficiency, whether these deficiencies are congenital or acquired (e.g. secondary to malignancy, infection, or irradiation).
Patients who are taking medications known to affect GnRH secretion, such as corticosteroids or continuous opiate administration (or were taking them at the time of diagnosis).

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Research Triangle Park?

Yes, this clinical trial (NCT01500447) has an active research site in Research Triangle Park, NC that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Genetic Disorder Treatment Options in Research Triangle Park, NC

If you're searching for genetic disorder treatment options in Research Triangle Park, NC, this clinical trial (NCT01500447) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Research Triangle Park research site is actively enrolling participants for this clinical trial. You'll receive care from experienced genetic disorder specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all genetic disorder clinical trials near you to find additional studies recruiting in your area.

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