Ann Arbor, MINCT04867317Now EnrollingIRB Ready

Growth Hormone Deficiency Clinical Trial in Ann Arbor, MI

Access cutting-edge growth hormone deficiency treatment through this phase 3 clinical trial at a research site in Ann Arbor. Study-provided care at no cost to qualified participants.

Sponsored by VA Office of Research and Development

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Expert Care in Ann Arbor

Access growth hormone deficiency specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related growth hormone deficiency treatment provided free

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Check if you qualify for this growth hormone deficiency clinical trial in Ann Arbor, MI

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Ann Arbor

    Convenient for MI residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Ann Arbor site if eligible
  4. 4Begin participation

About This Growth Hormone Deficiency Study in Ann Arbor

The purpose of this study is to determine whether growth hormone replacement therapy (GHRT) is effective versus placebo in the improvement of Quality of Life in patients with adult growth hormone deficiency (AGHD) and mild traumatic brain injury (mTBI).

Sponsor: VA Office of Research and Development

Who Can Participate

Inclusion Criteria

OEF/OIF/OND Veteran
Score of 18 or more on Combat Experiences sub-scale of Deployment Risk and Resilience Inventory-2 (DRRI-2)
Age 21 - 55 years old
One or more mTBI sustained during military service at least 12 months prior to the screening date, as noted via the CRAFT survey.
GH deficiency diagnosed by: macimorelin stimulation test (cut point 5.1 mcg/L), or glucagon stimulation test (cut point: 3 mcg/L for BMI up to 25; cut point 1 mcg/L for BMI 25 and above) and IGF-I lab values have to be less than or equal to +1 SDS at baseline
Score of 11 or more on QoL-AGHDA
4-week stability on any psychotropic medications
3-month stability on all other hormone treatments
Able and willing to provide informed consent to participate in this study, and complete study protocol.

Exclusion Criteria

History of moderate or severe TBI
History of neurologic disorder other than TBI with substantial impact on quality of life
History of bipolar disorder, schizophrenia, or other concurrent psychotic disorder
Active suicidal ideation (no plan required) as determined by a score of 2 points or more on the Columbia Suicide Severity Rating Scale (C-SSRS) suicidal ideation rating, or overt suicidal behavior in the past 6 months.
Contraindication to rhGH therapy
Acute medical illness, active infection, cancer or decompensated chronic medical illness
Evidence of substance use disorder, -other than mild alcohol or cannabis use disorder-, or urine toxicology evidence of the use of an illicit drug (excluding cannabis), in the past 6 months. Nicotine use is allowed.
Score less than or equal to 41 on Trial 2 or Retention Trial of the Test of Memory and Malingering (TOMM).
BMI \> 40 or body weight \> 350 lbs
Pituitary anatomy documented by an MRI using a sella protocol within the last 2 years indicating abnormalities consistent with an etiology other than mild-TBI (i.e.; pituitary mass)
Women who are pregnant or of child-bearing potential not on contraception
Current use of the following: growth hormone, estrogen or estrogen-like dietary supplements, progestin, IGF-I, or chronic glucocorticoid use in supraphysiologic doses
Currently enrolled in any other interventional study unless prior approval is provided by the study chairs and the study sponsor (Cooperative Studies Program)

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Ann Arbor?

Yes, this clinical trial (NCT04867317) has an active research site in Ann Arbor, MI that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Growth Hormone Deficiency Treatment Options in Ann Arbor, MI

If you're searching for growth hormone deficiency treatment options in Ann Arbor, MI, this clinical trial (NCT04867317) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Ann Arbor research site is actively enrolling participants for this phase 3 clinical trial. You'll receive care from experienced growth hormone deficiency specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all growth hormone deficiency clinical trials near you to find additional studies recruiting in your area.

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