Is NCT06815991 recruiting in Boston, MA?

Yes, NCT06815991 is currently recruiting participants at its Boston, MA location. This healthy adults clinical trial is actively enrolling qualified participants.

How do I join the healthy adults clinical trial in Boston?

To join this clinical trial in Boston, complete the eligibility form on this page. A study coordinator will contact you to discuss next steps and determine if you qualify.

Is participation in this Boston clinical trial free?

Yes, all study-related care is provided at no cost to qualified participants. Many studies also offer compensation for time and travel expenses.

Healthy Adults Clinical Trial in Boston, MA

About This Healthy Adults Study in Boston

This is a single center, open label (i.e. participants and study staff will not be masked to the intervention) single ascending dose study to evaluate the safety, tolerability, pharmaokinetics and pharmacodynamics of MIB-725 in community dwelling, healthy adults. Up to 4 successive groups (cohorts) of 8 subjects each will be enrolled in this trial. This study will determine the safety and tolerability of orally administered single ascending (increasing) doses (100, 200, 400, and 800 mg) of MIB-725 in healthy adults. The safety will be assessed by evaluating physical examination that includes an external eye examination, vital signs, adverse events, and changes in blood counts, EKG, urinalysis, coagulation measures, and blood chemistries, including but not limited to blood glucose, electrolytes, creatinine, liver function tests, uric acid, and creatine kinase.

Sponsor: Metro International Biotech, LLC

Who Can Participate

Inclusion Criteria

Is a non-smoking healthy adult, 19 to 60 years of age, inclusive

Has a body mass index (BMI) between 19 and 37.5 kg/m2, inclusive

Is free from clinically significant medical problems as determined by the Investigator

Is able and willing to provide written informed consent.

Is able and willing to provide authorization for the use and disclosure of personal health information in accordance with the Health Insurance Portability and Accountability Act (HIPAA).

Exclusion Criteria

Is a current cigarette smoker

AST or ALT \> 1.5 times the upper limit of normal

Hematocrit \< 37% or \> 51%

Diagnosis of diabetes mellitus, as indicated by use of diabetes medication, hemoglobin A1C \> 6.4% or fasting glucose ≥126 mg/dL

Serum creatinine \> 2.0 mg/dL

Current use of barbiturates, benzodiazepines, opiates, amphetamine, cannabinoids and cocaine

Known allergy to niacin or nicotinamide mononucleotide

Unwilling to refrain from drinking alcohol during the duration of the study

Use of any other dietary supplement during the course of the trial

Use of anabolic steroids, rhGH, DHEA, androstenedione, or any other performance enhancing drug

In the judgment of the study physician, the participant is unlikely to comply with the study protocol for any reason or it may not be safe to administer the study medication

Has a history of myocardial infarction, stroke, or heart failure in the preceding 6 months.

Has a history of cancer other than nonmelanotic skin cancer requiring treatment in the previous 2 years.

Has other medical conditions which, in the opinion of the Principal Investigator, would jeopardize the safety of the study subject or impact the validity of the study results. In addition, female participants must:

Be postmenopausal as indicated by cessation of menstruation at least one year before screening

Not be pregnant and not planning to become pregnant over the next 6 months Prohibited medications and substances:

Current use of barbiturates, benzodiazepines, opiates, amphetamine, cannabinoids and cocaine

Use of any other dietary supplement during the course of the trial. Subjects who are using a supplement containing nicotinamide, niacin, nicotinamide mononucleotide, or nicotinamide riboside may be included if they agree to stop the supplement at least 2 weeks prior to day 0 and during the entire duration of the study.

Initiation of a new prescription drug during the preceding 4 weeks or during the course of the study

Use of anabolic steroids, rhGH, DHEA, androstenedione, or any other performance enhancing drug \-

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Boston?

Yes, this clinical trial (NCT06815991) has an active research site in Boston, MA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Healthy Adults Treatment Options in Boston, MA

If you're searching for healthy adults treatment options in Boston, MA, this clinical trial (NCT06815991) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Boston research site is actively enrolling participants for this clinical trial. You'll receive care from experienced healthy adults specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all healthy adults clinical trials near you to find additional studies recruiting in your area.

Healthy Adults Clinical Trial in Boston, MA

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