Is NCT06882096 recruiting in Boston, MA?

Yes, NCT06882096 is currently recruiting participants at its Boston, MA location. This healthy adults clinical trial is actively enrolling qualified participants.

How do I join the healthy adults clinical trial in Boston?

To join this clinical trial in Boston, complete the eligibility form on this page. A study coordinator will contact you to discuss next steps and determine if you qualify.

Is participation in this Boston clinical trial free?

Yes, all study-related care is provided at no cost to qualified participants. Many studies also offer compensation for time and travel expenses.

Healthy Adults Clinical Trial in Boston, MA

About This Healthy Adults Study in Boston

We are doing this research to learn how healthy younger and older adults use two forms of vitamin B3-called nicotinamide mononucleotide (NMN) and nicotinamide (NAM)-to make NAD+. NAD+ is a natural substance that cells need for energy and other important processes. Our goal is to find out how these NAD precursors are absorbed and metabolized and how they raise NAD+ in different tissues. Who can join? Healthy adults men and women aged 18 to 40 (younger group) or 65 and older (older group) Participants with a body mass index ranging between 19 and 35 No major health issues like diabetes or severe kidney disease What will happen? Participants will take labeled or unlabeled NMN or NAM by mouth every day for 14 days. Researchers will collect blood, urine, and stool samples. Researchers also do a small muscle biopsy (under local numbing) twice to check how these NAD precursors raise NAD+ in muscle. Why is this important? NAD+ levels may drop as people age, and this drop could affect overall health and energy in cells. A better understanding of how NMN and NAM are metabolized in the body to raise NAD+ levels in both younger and older adults may help us optimize dosing and strategies for raising NAD in older people. Possible benefits and risks: Participants may not get any direct health benefit from this study; the main goal is to gather new knowledge. NMN and NAM appear safe in the doses used. A muscle biopsy may cause soreness or bruising. Researchers will monitor participants closely for any side effects throughout the study.

Sponsor: Metro International Biotech, LLC

Who Can Participate

Inclusion Criteria

A participant may be enrolled if he/she is:

A healthy, community-living, man or a woman between 18 and 40 years, inclusive or 65 years or older

Has a body mass index (BMI) between 19 and 35 kg/m2, inclusive

Is free from clinically significant medical problems as determined by the Investigator

Is capable of providing written informed consent.

Is willing and able to provide authorization for the use and disclosure of personal health information in accordance with Health Insurance Portability and Accountability Act.

Exclusion Criteria

A subject may not be enrolled if s/he:

Has AST or ALT \> 2 times the upper limit of normal

Hematocrit \< 36% or \> 51% for men, or \< 35% to \> 48% for women

Diagnosis of diabetes, using diabetes medications or an A1C \> 6.4%

Serum creatinine \> 2.0 mg/dL or eGFR \<60 mL/min

Prohibited medications and substances: use of anabolic steroids, rhGH, DHEA, androstenedione, or any performance enhancing drug; Current use of opiates, amphetamine, cannabinoids and cocaine

Use of any dietary supplement. Subjects who are using a supplement containing NAM (or niacin or NMN or NR) may be included if they agree to stop supplement at least 2 weeks before randomization.

For women only: Pregnant or planning to get pregnant over the next 6 months, or lactating

Participation in an investigational trial within the past 3 months

Other medical conditions which, in the opinion of the investigator, would jeopardize safety or impact the validity of the study results For women only: Female of childbearing age: Use of oral contraceptives is allowed provided the contraceptive regimen was initiated at least 3 months before randomization and the participant agrees not to change the regimen during the course of the study. Excluded Medications and Treatments

The ingestion of the following is prohibited during 14 days prior to Day 0 and for the duration of the intervention period:

Products that contain niacin, nicotinic acid, nicotinamide in any form, other than natural foods

Herbal supplements

Treatment with another investigational drug, investigational device, or approved therapy for investigational use within 3 month is prohibited.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Boston?

Yes, this clinical trial (NCT06882096) has an active research site in Boston, MA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Healthy Adults Treatment Options in Boston, MA

If you're searching for healthy adults treatment options in Boston, MA, this clinical trial (NCT06882096) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Boston research site is actively enrolling participants for this clinical trial. You'll receive care from experienced healthy adults specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all healthy adults clinical trials near you to find additional studies recruiting in your area.

Healthy Adults Clinical Trial in Boston, MA

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