Charlottesville, VANCT05685108Now EnrollingIRB Ready

Healthy Subjects Clinical Trial in Charlottesville, VA

Access cutting-edge healthy subjects treatment through this clinical trial at a research site in Charlottesville. Study-provided care at no cost to qualified participants.

Sponsored by University of Virginia

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Expert Care in Charlottesville

Access healthy subjects specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related healthy subjects treatment provided free

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Check if you qualify for this healthy subjects clinical trial in Charlottesville, VA

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Charlottesville

    Convenient for VA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Charlottesville site if eligible
  4. 4Begin participation

About This Healthy Subjects Study in Charlottesville

This is a feasibility study to determine whether pulsed ultrasound stimulation targeting the splenic nerve or the cervical vagus nerve can elicit an anti-inflammatory immune response in healthy volunteers.

Sponsor: University of Virginia

Who Can Participate

Inclusion Criteria

Male or female, aged 25-50 years
Provision of signed and dated informed consent form
Able to comprehend the study goals and procedures, stated willingness to comply with all study procedures, and availability for the duration of the study
Considered English proficient so that the subject can follow verbal commands during the ultrasound procedure
In good general health, as evidenced by medical history
Laboratory results indicating normal blood count and adequate organ function
Agreement to adhere to Lifestyle Considerations throughout study duration.

Exclusion Criteria

Chronic medical conditions, including cancer (in remission or active cancer), cerebrovascular disease, chronic kidney disease, heart conditions (such as heart failure, coronary artery disease, cardiomyopathies), lung disease, liver disease, hypertension, diabetes mellitus type 1 and 2, human immunodeficiency virus infection, primary immunodeficiencies, solid organ or hematopoietic cell transplantation, tuberculosis, and cystic fibrosis, autoimmune disorders (e.g., rheumatoid arthritis, inflammatory bowel disease), sickle cell anemia or other anemia syndromes
Mean systolic and diastolic blood pressure values during screening of ≥160 and ≥100 mm Hg, respectively, hypertension on non-selective beta-blockers and/or alpha-methyl dopa, or hypertension requiring more than two anti-hypertension medications
Obesity (body mass index ≥30 kg/m2)
Use of anti-inflammatory or immunomodulatory medication, such as non- steroidal anti-inflammatory drugs (NSAIDs), corticosteroids, or other immunosuppressants, within one week of receiving ultrasound delivery
Use of anticoagulant drugs (e.g., coumadin, direct oral anticoagulants) or antiplatelet drugs (e.g., aspirin, clopidogrel) within one week of receiving ultrasound delivery
Pregnancy, breastfeeding, or planning to become pregnant during the study
Active bacterial or viral infection; febrile illness within 2 weeks of receiving ultrasound delivery
Known allergic reactions to ultrasound gel
Treatment with another investigational drug or other intervention within 1 month of receiving ultrasound delivery
Any vaccination received within 1 month of receiving ultrasound delivery
Current smoker or nicotine use within 2 weeks of receiving ultrasound delivery
Use of recreational drugs within 2 weeks of receiving ultrasound delivery
History of arrythmia (e.g., clinically significant bradycardia, atrial flutter, atrial fibrillation, ventricular arrythmias)
History of deep vein thrombosis or pulmonary embolism
History of bleeding disorder
History of seizure
History of unilateral or bilateral vagotomy
Participants with an implantable medical device, such as pacemaker, hearing aid implant, or any implanted electronic device
Surgery or traumatic injury (e.g., visceral injury, cerebral injury) in the past 3 months
Prior surgery on thyroid or parathyroid glands, esophagus, stomach, or spleen
Participant is considered by the Investigator, after reviewing medical and psychiatric history, physical examination, and laboratory evaluations, to be unsuitable for any other reason that may either place the patient at increased risk during participation or interfere with the interpretation of the study. outcomes.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Charlottesville?

Yes, this clinical trial (NCT05685108) has an active research site in Charlottesville, VA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Healthy Subjects Treatment Options in Charlottesville, VA

If you're searching for healthy subjects treatment options in Charlottesville, VA, this clinical trial (NCT05685108) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Charlottesville research site is actively enrolling participants for this clinical trial. You'll receive care from experienced healthy subjects specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all healthy subjects clinical trials near you to find additional studies recruiting in your area.

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