NCT07526571 · University of North Carolina, Chapel Hill
GLOW Study: Effects of Triple Protein in Women
What this study is about
This single-site, randomly assigned, blinded, compared against an inactive treatment study will evaluate whether 4 weeks of daily Triple Support Protein powder improves glycemic control and overall well-being in healthy women aged 30-60 years.
View original scientific description
This single-site, randomized, blinded, placebo-controlled study will evaluate whether 4 weeks of daily Triple Support Protein powder improves glycemic control and overall well-being in healthy women aged 30-60 years. Participants will undergo baseline testing (DXA, fasting blood, standardized meal test with 2-hour glucose and insulin sampling), complete one acute supervised dose, and then consume a daily supplement for 4 weeks. During the final 14 days, participants will wear a continuous glucose monitor. Outcomes include postprandial glucose AUC, insulin sensitivity, and body composition.
Interventions
DIETARY_SUPPLEMENT
Triple protein support
Plant based protein + creatine + fiber
DIETARY_SUPPLEMENT
Placebo
Non-caloric matched placebo
Primary outcome measures
Change in postprandial glucose area under the curve (AUC)
Time frame: Glucose measured over 0-120 minutes starting post standardized meal
Glucose measured at 0-120 minutes post-meal; AUC by trapezoidal method.
Who can participate
This study lists these criteria on ClinicalTrials.gov. A study coordinator reviews eligibility during screening — this page does not determine whether you qualify.
Inclusion criteria
- Females aged 30-60 years.
- BMI 18.5-40 kg/m\^2.
- Recreationally active (≥30 min/wk moderate intensity exercise).
- Healthy and free from disease per health history questionnaire.
- Willing to abstain from caffeine, tobacco, and alcohol for 24 hours before testing days.
Exclusion criteria
- Currently supplementing whey protein.
- Pregnant or nursing.
- Lactose intolerant.
- Currently using creatine monohydrate.
- Severe hearing or speech impairment or inability to speak English
Where
- Chapel Hill, North Carolina
Collaborators
Perelel Inc.
Related conditions & keywords
Frequently asked questions
What is a clinical trial?
A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.
Is it safe to participate?
Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.
Will I be compensated?
Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.
Will I receive a placebo instead of treatment?
When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.
Can I leave a trial if I change my mind?
Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.
How long does a clinical trial last?
Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.
Data: ClinicalTrials.gov · synced Apr 13, 2026 · Source of record for eligibility and locations