NCT06860152 · Craig D. Workman, PhD
Cochlear Implant Speech in Noise Processing
What this study is about
The study will help us in understanding the neural mechanisms by which listeners with a cochlear implant detect speech in noisy environments.
View original scientific description
The study will help us in understanding the neural mechanisms by which listeners with a cochlear implant detect speech in noisy environments.
Who can participate
This study lists these criteria on ClinicalTrials.gov. A study coordinator reviews eligibility during screening — this page does not determine whether you qualify.
Inclusion criteria
- Between 18 and 99 years of age.
- Have a cochlear implant activated for more than one year.
- Eligible for research under the Iowa Cochlear Implant Project VIII.
- Ability to understand and willingness to sign a written informed consent document.
- Severe hearing loss after age 16. Normal Hearing subjects (enrollment is planned at N=30) - Inclusion criteria:
- Between 18 and 99 years of age.
- Have age typical hearing.
- Eligible for research under the Iowa Cochlear Implant Project VIII.
- Ability to understand and willingness to sign a written informed consent document.
Exclusion criteria
- (all groups):
- Medical history includes seizure disorder, head injury, neurologic, metabolic, cardiovascular disease, or previous cerebrovascular event (unless approved by PI).
- Female self-reporting pregnancy. A urine pregnancy test will be performed prior to injection of the radiopharmaceutical.
- Currently taking medications which may affect cerebral blood flow (e.g., papaverine, ginkgo biloba, acetazolamide).
- Uncontrolled intercurrent illness that would limit compliance with study requirements per investigator.
Where
- Iowa City, Iowa
Frequently asked questions
What is a clinical trial?
A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.
Is it safe to participate?
Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.
Will I be compensated?
Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.
Will I receive a placebo instead of treatment?
When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.
Can I leave a trial if I change my mind?
Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.
How long does a clinical trial last?
Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.
Data: ClinicalTrials.gov · synced May 14, 2026 · Source of record for eligibility and locations