Morgantown, WVNCT05537896Now EnrollingIRB Ready

Hematological Malignancy Clinical Trial in Morgantown, WV

Access cutting-edge hematological malignancy treatment through this phase 2 clinical trial at a research site in Morgantown. Study-provided care at no cost to qualified participants.

Sponsored by West Virginia University

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Expert Care in Morgantown

Access hematological malignancy specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related hematological malignancy treatment provided free

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Check if you qualify for this hematological malignancy clinical trial in Morgantown, WV

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Morgantown

    Convenient for WV residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Morgantown site if eligible
  4. 4Begin participation

About This Hematological Malignancy Study in Morgantown

Antibacterial prophylaxis is recommended in patients at high risk of infection, specifically patients undergoing acute leukemia induction therapy or hematopoietic stem cell transplant (HSCT) who are expected to have profound neutropenia (ANC\<100 neutrophils/milliliter) for more than seven days. Xerava™ (eravacycline) has a broad spectrum of activity including many multi-drug resistant strains of bacteria. It is not an agent used for treatment of febrile neutropenia, making eravacycline a very attractive alternative to consider in this prophylactic setting. Eravacycline has activity against MRSA, VRE, and Clostridioides difficile, all of which are common problems in this patient population. It also covers the majority of enteric gram-negative pathogens while also producing satisfactory tissue penetration and adequate plasma concentrations, which has classically been a concern with prior agents. Eravacycline has activity against coagulase-negative staphylococcus, which is a common catheter-related infection in leukemia and HSCT patients. The primary objective will be report the incidence of breakthrough infections during eravacycline prophylaxis for hematologic malignancy patients with prolonged neutropenia.

Sponsor: West Virginia University

Who Can Participate

Inclusion Criteria

All patients receiving induction chemotherapy for treatment of acute leukemia or receiving preparative regimen for HSCT
Patient must provide informed consent.
Bilirubin ≤ 3 x the ULN and AST/ALT ≤ 5 x ULN

Exclusion Criteria

Uncontrolled bacterial, viral or fungal infection at the time of study enrollment.
Urinary tract infection receiving active treatment
Acute pancreatitis (not necessary to work-up unless symptomatic)
History of known hypersensitivity to eravacycline, tetracycline, doxycycline, minocycline, tigecycline, sarecycline, oxytetracycline, or omadacycline
Pseudomonas infection within 30 days prior to study enrollment
Receiving strong inhibitors or inducers of cytochrome P450 3A4 will be excluded from the study (see Appendix B for complete list of medications)
Pregnant or lactating women

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Morgantown?

Yes, this clinical trial (NCT05537896) has an active research site in Morgantown, WV that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Hematological Malignancy Treatment Options in Morgantown, WV

If you're searching for hematological malignancy treatment options in Morgantown, WV, this clinical trial (NCT05537896) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Morgantown research site is actively enrolling participants for this phase 2 clinical trial. You'll receive care from experienced hematological malignancy specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all hematological malignancy clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Morgantown, WV