Little Rock, ARNCT07582276Now EnrollingIRB Ready

Hemophilia a Clinical Trial in Little Rock, AR

Access cutting-edge hemophilia a treatment through this clinical trial at a research site in Little Rock. Study-provided care at no cost to qualified participants.

Sponsored by Arkansas Children's Hospital Research Institute

Quick Self-Assessment

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Expert Care in Little Rock

Access hemophilia a specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related hemophilia a treatment provided free

Apply for This Little Rock Location

Check if you qualify for this hemophilia a clinical trial in Little Rock, AR

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Little Rock

    Convenient for AR residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Little Rock site if eligible
  4. 4Begin participation

About This Hemophilia a Study in Little Rock

This study will compare bone mineral density in patients with severe hemophilia A receiving prophylaxis with emicizumab or efanesoctocog alfa. Participants will undergo assessments of bone mineral density, bone remodeling biomarkers, thrombin generation, plasmin generation, and joint health over a five-year period. The study aims to evaluate whether differences in prophylactic therapy are associated with differences in bone health outcomes.

Sponsor: Arkansas Children's Hospital Research Institute

Who Can Participate

Inclusion Criteria

The participant or legally authorized representative is willing and able to provide written informed consent.
Diagnosis of severe hemophilia A (factor VIII activity \< 1%).
Age between 30 and 50 years (inclusive).
BMI between 18.5 and 40 kg/m2
The participant must have been on prophylaxis with Efanesoctocog alfa or Emicizumab for at least 3 months prior to enrollment and intend to remain on the current regimen for the next 5 years.
Willingness to undergo all research procedures, including DEXA scans and the collection of blood samples.
Willingness to complete all standard-of-care bleeding and treatment logs.

Exclusion Criteria

Unwillingness of the participant, parent, or legally authorized representative to provide informed consent.
Diagnosis of a bleeding disorder other than or in addition to severe hemophilia A.
Active Factor VIII inhibitors at the time of enrollment
History of a disease known to influence bone metabolism unrelated to a bleeding disorder. (Examples: Paget's disease, osteogenesis imperfecta, Ehlers Danlos syndrome, Hyperparathyroidism)
Past or present treatment with any anti-osteoporotic medication, excluding oral vitamin D or oral calcium supplements.
Documented HIV infection or HCV infection (whether in progress or cured) at the cirrhotic stage.
Presence of a non-removable metal device that would interfere with research procedures.
Inability to tolerate a DEXA scan due to limited range of motion or body habitus.
History of bone fractures or surgical repair within 8 weeks prior to enrollment.
Participants with weight \>300 pounds, due to limitations of DEXA scanner

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Little Rock?

Yes, this clinical trial (NCT07582276) has an active research site in Little Rock, AR that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Hemophilia a Treatment Options in Little Rock, AR

If you're searching for hemophilia a treatment options in Little Rock, AR, this clinical trial (NCT07582276) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Little Rock research site is actively enrolling participants for this clinical trial. You'll receive care from experienced hemophilia a specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all hemophilia a clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Little Rock, AR