Miami, FLNCT05959291Now EnrollingIRB Ready

HER2-positive Metastatic Breast Cancer Clinical Trial in Miami, FL

Access cutting-edge her2-positive metastatic breast cancer treatment through this clinical trial at a research site in Miami. Study-provided care at no cost to qualified participants.

Sponsored by University of Miami

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Preparing your pre-screening questions…

Expert Care in Miami

Access her2-positive metastatic breast cancer specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related her2-positive metastatic breast cancer treatment provided free

Apply for This Miami Location

Check if you qualify for this her2-positive metastatic breast cancer clinical trial in Miami, FL

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Miami

    Convenient for FL residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Miami site if eligible
  4. 4Begin participation

About This HER2-positive Metastatic Breast Cancer Study in Miami

The purpose of this preliminary research study is to see if patients discontinuing maintenance Herceptin and/or other anti-HER-2 treatments with monitoring in addition to radiologic imaging and routine blood work will stay in complete radiological remission and to determine how long patients are able to stay in complete radiological remission without treatment.

Sponsor: University of Miami

Who Can Participate

Inclusion Criteria

Patients with a diagnosis of HER-2 positive metastatic (Stage IV) breast cancer.
Patients in complete radiological remission (CRR), including a stable bone scan, as determined by computed tomography (CT), positron-emission tomography (PET), or PET-CT. a. Patients with brain metastasis are allowed to participate as long as their disease has been treated and radiologically stable for at least 36 months.
Patients must be on the same or current anti-HER-2 directed therapy for at least 36 months.
Archived tumor biopsy available.
Patients with no evidence of circulating tumor deoxyribonucleic acid (ctDNA) as determined by the Signatera assay.
Patients willing to stop maintenance anti-HER-2 directed therapy with close monitoring.
Patients with an Eastern Cooperative Oncology Group (ECOG) performance score from 0 to 2.
Patients ≥ 18 years of age.
Ability to understand and the willingness to sign a written informed consent document.

Exclusion Criteria

Patients with uncontrolled metastatic disease.
Patients whose disease has been controlled for less than 36 months on the same or current anti-HER-2 therapy.
Patients who are currently receiving or have received treatment for a secondary cancer other than resected non-melanoma skin cancer lesions or in situ cancer within the past 24 months.
Patients positive for ctDNA (which occurs when a patient's blood sample contains ≥2 target markers) with the Signatera assay.
Use of investigational drugs ≤ 28 days prior to study enrollment and during the study.
History or current evidence of any condition, therapy, or laboratory abnormality that might confound the results of the trial, interfere with the patient's participation for the full duration of the trial, or that makes participation in the trial to be not in the best interest of the patient in the opinion of the Investigator.
Patients with impaired decision-making capacity. Patients who are found to be ctDNA+ at study entry will be recorded as a screen failure (Section 5.4). Their Signatera testing results will be provided to their treating physician to aid in clinical decision-making for disease management and treatment.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Miami?

Yes, this clinical trial (NCT05959291) has an active research site in Miami, FL that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

HER2-positive Metastatic Breast Cancer Treatment Options in Miami, FL

If you're searching for her2-positive metastatic breast cancer treatment options in Miami, FL, this clinical trial (NCT05959291) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Miami research site is actively enrolling participants for this clinical trial. You'll receive care from experienced her2-positive metastatic breast cancer specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all her2-positive metastatic breast cancer clinical trials near you to find additional studies recruiting in your area.

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