Is NCT05846451 recruiting in Spokane, WA?

Yes, NCT05846451 is currently recruiting participants at its Spokane, WA location. This herbal interaction clinical trial is actively enrolling qualified participants.

How do I join the herbal interaction clinical trial in Spokane?

To join this clinical trial in Spokane, complete the eligibility form on this page. A study coordinator will contact you to discuss next steps and determine if you qualify.

Is participation in this Spokane clinical trial free?

Yes, all study-related care is provided at no cost to qualified participants. Many studies also offer compensation for time and travel expenses.

Herbal Interaction Clinical Trial in Spokane, WA

About This Herbal Interaction Study in Spokane

The goal of this study is to investigate whether the botanical product kratom affects how the body processes the opioid drug oxycodone. The main research questions to be answered are two-fold: 1. How does kratom affect the manner in which oxycodone is metabolized (broken down and removed) by the body? 2. Does kratom change the effects oxycodone exerts on the body? Healthy adult participants will complete four study arms, during which they will be given the following: * Kratom (as a tea) * A single dose of oxycodone (as a tablet) * Kratom tea and a single dose of oxycodone * Kratom tea for four days, then kratom tea and a single dose of oxycodone

Sponsor: Washington State University

Who Can Participate

Inclusion Criteria

Males and females, aged from 21-45 years and healthy

Body weight between 130 and 250 pounds (60-115 kg) and body mass index between 19 and 30

Not taking any medications (prescription and non-prescription) or dietary supplements/botanical products known to alter the pharmacokinetics of either oxycodone or kratom

Willing to abstain from consuming dietary supplements/botanical products and fruit juices for several weeks

Willing to abstain from cannabis/marijuana, hemp, and THC- and/or CBD-containing products for several weeks

Willing to abstain from consuming caffeinated beverages or other caffeine-containing products the evening before and morning of any inpatient visit

Willing to abstain from consuming alcoholic beverages for one day prior to any inpatient visit

Willing to use an additional method of contraception that does not include oral contraceptive pills, patches, or other hormonal methods (such as abstinence, copper IUD, or condoms)

Have consumed kratom previously and tolerated it well without any unpleasant effects

Willing to abstain from kratom for several weeks

Have consumed any opioid previously and tolerated it well without any unpleasant effects or addiction

Written informed consent (and assent when applicable) obtained from subject or subject's legal representative and ability for the subject to comply with the requirements of the study

Geographically located within a 40-mile radius of Spokane and have the time to participate

Exclusion Criteria

Males and females under the age of 21 or over the age of 45

People who weigh less than 130 pounds or more than 250 pounds

People with a body mass index less than 19 or greater than 30

Any current major illness or chronic illness including but not limited to kidney disease, hepatic disease, diabetes mellitus, hypertension, coronary artery disease, chronic obstructive pulmonary disease, cancer, or HIV/AIDS

No previous exposure to kratom

No previous exposure to an opioid

History of anemia or any other significant hematologic disorder

History of substance abuse, dependence, or addiction or major psychiatric illness

A need for chronic opioid analgesics

Use of opioid analgesics 3 weeks prior to initiation of the study

An imminent likely need for opioid analgesics (e.g., planned dental or surgical procedure)

Pregnant or nursing

History of allergy or intolerance to kratom, other opioids, or oxycodone

Taking concomitant medications, both prescription and non-prescription (including dietary supplements/botanical products), known to alter the pharmacokinetics of kratom or oxycodone

Presence of a condition or abnormality that, in the opinion of the Investigator, would compromise the safety of the patient or the quality of the data

History of sleep apnea

Any prior use of amphetamines, benzodiazepines, cocaine, MDMA, opioids, PCP, or other drugs for recreational purposes

Use of cannabis/marijuana, hemp, THC-containing products, CBD-containing products, or CBD within the last month

Out-of-range clinical laboratory value that the study physician considers participation in the study a health risk

Inability to speak, read, and understand English

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Spokane?

Yes, this clinical trial (NCT05846451) has an active research site in Spokane, WA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Herbal Interaction Treatment Options in Spokane, WA

If you're searching for herbal interaction treatment options in Spokane, WA, this clinical trial (NCT05846451) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Spokane research site is actively enrolling participants for this early phase 1 clinical trial. You'll receive care from experienced herbal interaction specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all herbal interaction clinical trials near you to find additional studies recruiting in your area.

Herbal Interaction Clinical Trial in Spokane, WA

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