St Louis, MONCT06659640Now EnrollingIRB Ready

Hereditary Hemorrhagic Telangiectasia Clinical Trial in St Louis, MO

Access cutting-edge hereditary hemorrhagic telangiectasia treatment through this clinical trial at a research site in St Louis. Study-provided care at no cost to qualified participants.

Sponsored by Alnylam Pharmaceuticals

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Expert Care in St Louis

Access hereditary hemorrhagic telangiectasia specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related hereditary hemorrhagic telangiectasia treatment provided free

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Check if you qualify for this hereditary hemorrhagic telangiectasia clinical trial in St Louis, MO

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Why Participate?

  • No-Cost Study Care

  • Local to St Louis

    Convenient for MO residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit St Louis site if eligible
  4. 4Begin participation

About This Hereditary Hemorrhagic Telangiectasia Study in St Louis

The purpose of this study is to: * evaluate the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of single ascending doses of ALN-6400 in healthy volunteers * evaluate the efficacy, safety, tolerability and PD of multiple doses of ALN-6400 in adult patients with HHT

Sponsor: Alnylam Pharmaceuticals

Who Can Participate

Inclusion Criteria

Is a healthy adult volunteer Part B:
Is an adult patient with a clinical diagnosis of HHT

Exclusion Criteria

Has alanine aminotransferase (ALT) or aspartate aminotransferase (AST) \> upper limit of normal (ULN)
Has known human immunodeficiency virus (HIV) infection; or known current or chronic hepatitis C virus or hepatitis B virus infection
Has an estimated glomerular filtration (eGFR) of \<90 mL/min/1.73m\^2 at screening Part B:
Has ALT or AST \>2×ULN
Has total bilirubin \>1.5×ULN
Has eGFR of \<30 mL/min/1.73m\^2 at screening Parts A and B:
Is not willing to comply with the contraceptive requirements during the study period Note: other protocol defined inclusion / exclusion criteria apply

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in St Louis?

Yes, this clinical trial (NCT06659640) has an active research site in St Louis, MO that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Hereditary Hemorrhagic Telangiectasia Treatment Options in St Louis, MO

If you're searching for hereditary hemorrhagic telangiectasia treatment options in St Louis, MO, this clinical trial (NCT06659640) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our St Louis research site is actively enrolling participants for this clinical trial. You'll receive care from experienced hereditary hemorrhagic telangiectasia specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all hereditary hemorrhagic telangiectasia clinical trials near you to find additional studies recruiting in your area.

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