Lexington, KYNCT07417943Now EnrollingIRB Ready

Hereditary Spastic Paraplegia Clinical Trial in Lexington, KY

Access cutting-edge hereditary spastic paraplegia treatment through this clinical trial at a research site in Lexington. Study-provided care at no cost to qualified participants.

Sponsored by Rahul Sachdeva

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Expert Care in Lexington

Access hereditary spastic paraplegia specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related hereditary spastic paraplegia treatment provided free

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Check if you qualify for this hereditary spastic paraplegia clinical trial in Lexington, KY

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Why Participate?

  • No-Cost Study Care

  • Local to Lexington

    Convenient for KY residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Lexington site if eligible
  4. 4Begin participation

About This Hereditary Spastic Paraplegia Study in Lexington

Hereditary spastic paraplegia (HSP) is a rare neurological condition that causes stiffness, weakness, and difficulty walking due to damage in the nerves that control movement. This study will test whether a noninvasive form of spinal cord stimulation, called transcutaneous spinal cord stimulation (tSCS), can improve walking and reduce muscle stiffness in adults with HSP. In this study, participants will receive tSCS twice a week for 8 weeks. The stimulation is delivered through self-adhesive electrodes placed on the skin over the lower back and does not require surgery. Each session will last about one hour. After the treatment period, participants will be followed for an additional 8 weeks without stimulation to see whether any improvements are maintained. Researchers will measure walking speed, walking endurance, muscle stiffness, and overall disease severity. Additional tests will explore changes in bladder and bowel function and muscle strength.

Sponsor: Rahul Sachdeva

Who Can Participate

Inclusion Criteria

Clinical diagnosis of hereditary spastic paraplegia (genetic confirmation if available).
Stable medications for spasticity and other neurologic symptoms for =4 weeks prior to enrollment.
Able to participate in study visits and assessments with or without assistive devices.
If ambulatory: able to walk at least 10 meters with or without an assistive device.
If wheelchair user: able to perform seated mobility tasks and transfers required for assessments.
Capacity to provide informed consent and follow study procedures, with an ability to communicate and understand instructions in English

Exclusion Criteria

Implanted electronic devices (e.g., pacemaker, deep brain stimulator, intrathecal pumps).
Severe cardiopulmonary disease that would make participation unsafe.
Open skin lesions or severe dermatologic conditions at electrode sites.
Pregnancy or plans to become pregnant during the intervention period.
Diagnosed with Primary Lateral Sclerosis (PLS) or another neurological condition that affects walking, such as stroke, multiple sclerosis (MS), or a recent surgery on legs.
Unable to participate in basic movement or mobility assessments, even with their usual mobility device (such as a wheelchair, walker, or cane). People who use wheelchairs or other mobility aids can participate if they can complete the study's mobility assessments in their usual way.
Cognitive or psychiatric conditions that make it difficult to give informed consent or follow study instructions.
Diagnosed with Urinary Tract Infection (UTI), either acute or ongoing, before or at the time of study enrollment.
Diagnosed with epilepsy.
Participation in another interventional clinical trial that could affect mobility or spasticity during the study.
A recent change (within the last 4 weeks) in medications or treatments that affect spasticity or movement (for example: baclofen, tizanidine, botulinum toxin injections).
Expect to start or change treatments for spasticity or mobility during the study period.
Any condition judged by the investigator to pose excess risk or confound outcomes.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Lexington?

Yes, this clinical trial (NCT07417943) has an active research site in Lexington, KY that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Hereditary Spastic Paraplegia Treatment Options in Lexington, KY

If you're searching for hereditary spastic paraplegia treatment options in Lexington, KY, this clinical trial (NCT07417943) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Lexington research site is actively enrolling participants for this clinical trial. You'll receive care from experienced hereditary spastic paraplegia specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all hereditary spastic paraplegia clinical trials near you to find additional studies recruiting in your area.

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