NCT06855498 · Incyte Corporation
Rollover Study for Participants Previously Enrolled in Clinical Trials of Povorcitinib
(STOP-LTR)
What this study is about
Rollover study for participants from predetermined, Incyte-sponsored parent clinical trials of povorcitinib.
View original scientific description
Rollover study for participants from predetermined, Incyte-sponsored parent clinical trials of povorcitinib.
Interventions
DRUG
povorcitinib
Study drug will be taken orally as defined by the protocol.
Primary outcome measures
Proportion of participants with Treatment-Emergent Adverse Events (TEAEs)
Time frame: Up to approximately 3 years
Adverse events either reported for the first time in this Protocol or any AE ongoing and defined as treatment-emergent from the parent Protocol.
Who can participate
This study lists these criteria on ClinicalTrials.gov. A study coordinator reviews eligibility during screening — this page does not determine whether you qualify.
Inclusion criteria
- Ability to comprehend and willingness to sign a written ICF for the study.
- Completed the treatment period of a predetermined, Incyte-sponsored, povorcitinib parent study without safety or tolerability concerns, per investigator's assessment.
- Received clinical benefit from treatment with study drug during the parent study, as determined by the investigator.
- Demonstrated compliance, as assessed by the investigator, with the parent Protocol requirements.
- Willingness to avoid pregnancy or fathering children as defined in the protocol.
- Willingness and ability to comply with the study Protocol and procedures.
Exclusion criteria
- Had been permanently discontinued from study treatment during the parent study.
- Had temporary study drug interruption due to safety and/or efficacy reasons at or after the final visit of the parent study.
- Received at least 1 dose of either of the following therapies within the 28 days prior to starting treatment in this rollov
Where
- Birmingham, Alabama
- Montgomery, Alabama
- Phoenix, Arizona
- Scottsdale, Arizona
- Tucson, Arizona
- Fayetteville, Arkansas
- Rogers, Arkansas
- Fountain Valley, California
- Fremont, California
- Huntington Beach, California
- Laguna Niguel, California
- Los Angeles, California
And 75 more locations — see the full list below.
Related conditions & keywords
Frequently asked questions
What is a clinical trial?
A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.
Is it safe to participate?
Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.
Will I be compensated?
Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.
Will I receive a placebo instead of treatment?
When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.
Can I leave a trial if I change my mind?
Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.
How long does a clinical trial last?
Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.
Data: ClinicalTrials.gov · synced Jul 6, 2026 · Source of record for eligibility and locations