Boston, MANCT07335289Now EnrollingIRB Ready

HIV Pre-exposure Prophylaxis Use Clinical Trial in Boston, MA

Access cutting-edge hiv pre-exposure prophylaxis use treatment through this clinical trial at a research site in Boston. Study-provided care at no cost to qualified participants.

Sponsored by Massachusetts General Hospital

Quick Self-Assessment

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Expert Care in Boston

Access hiv pre-exposure prophylaxis use specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related hiv pre-exposure prophylaxis use treatment provided free

Apply for This Boston Location

Check if you qualify for this hiv pre-exposure prophylaxis use clinical trial in Boston, MA

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Boston

    Convenient for MA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Boston site if eligible
  4. 4Begin participation

About This HIV Pre-exposure Prophylaxis Use Study in Boston

PrEP4U is designed as a pragmatic, randomized implementation trial to test strategies that could directly inform real-world roll-out of lenacapavir. By integrating: * Same-day initiation based on rapid HIV testing, and * Choice of follow-up delivery location (home, community, or clinic) the study addresses two of the most pressing implementation questions for long-acting injectable PrEP. The primary hypothesis is that giving participants choice in follow-up location will improve PrEP persistence compared to a clinic-only model. Secondary analyses will evaluate safety of rapid testing, acceptability, and participant costs. Exploratory analyses will assess HIV incidence and resistance. Findings from PrEP4U will provide essential evidence to guide scalable, equitable, person-centered delivery models for lenacapavir PrEP in the U.S. and globally.

Sponsor: Massachusetts General Hospital

Who Can Participate

Inclusion Criteria

HIV negative
Eligible for HIV PrEP per CDC guidelines
Able and willing to provide informed consent
Willing to receive injectable lenacapavir and adhere to study procedures
Residing inMassachusetts with expected availability for 6-month follow-up

Exclusion Criteria

Known HIV infection at baseline
Contraindication to lenacapavir injection (e.g., hypersensitivity, significant drug interactions)
Pregnancy at baseline (participants who become pregnant during the trial may remain enrolled if they choose)
Participation in another interventional HIV prevention study
Any condition judged by the investigator to compromise safety or study integrity

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Boston?

Yes, this clinical trial (NCT07335289) has an active research site in Boston, MA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

HIV Pre-exposure Prophylaxis Use Treatment Options in Boston, MA

If you're searching for hiv pre-exposure prophylaxis use treatment options in Boston, MA, this clinical trial (NCT07335289) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Boston research site is actively enrolling participants for this clinical trial. You'll receive care from experienced hiv pre-exposure prophylaxis use specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all hiv pre-exposure prophylaxis use clinical trials near you to find additional studies recruiting in your area.

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