Nashville, TNNCT07221214Now EnrollingIRB Ready

HIV Clinical Trial in Nashville, TN

Access cutting-edge hiv treatment through this clinical trial at a research site in Nashville. Study-provided care at no cost to qualified participants.

Sponsored by Vanderbilt University Medical Center

Quick Self-Assessment

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Expert Care in Nashville

Access hiv specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related hiv treatment provided free

Apply for This Nashville Location

Check if you qualify for this hiv clinical trial in Nashville, TN

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Nashville

    Convenient for TN residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Nashville site if eligible
  4. 4Begin participation

About This HIV Study in Nashville

The goal of this clinical trial is to learn if the drug semaglutide works to reduce alcohol intake among adults living with HIV. The main questions it aims to answer are: 1. Does semaglutide lower the average number of alcoholic beverages participants drink per week? 2. Does semaglutide lower the average number of cigarettes participants smoke per day? 3. Does semaglutide decrease the risk for cardiovascular disease among people living with HIV who drink alcohol and/or smoke tobacco? Researchers will compare the effects of semaglutide to a placebo (a look-alike substance that contains no drug) to see if semaglutide works to lower the alcohol intake among participants each week. Participants will: 1. Take semaglutide for 3 months 2. Visit the research clinic 3 times for checkups and tests 3. Provide blood samples, stool samples, and saliva samples for tests.

Sponsor: Vanderbilt University Medical Center

Who Can Participate

Inclusion Criteria

Prior diagnosis of HIV-1
Affiliated with Vanderbilt Comprehensive Care Clinic
On current ART regimen for at least 90 days prior to study entry with no missed doses for at least 7 consecutive days.
Most recent absolute CD4 count ≥ 300 cells/mm3 and drawn within 12 months of study enrollment
BMI ≥ 23 (calculated at screening)
Self-report of consuming alcohol in past 90 days
AUDIT-C ≥ 3 (male)/ ≥ 2 (female)
Has an established stable address at which they can receive mail and can be reached for the next 6 months
Willing and able to complete study procedures and follow-ups

Exclusion Criteria

Known allergy to semaglutide
Currently taking GLP-1 RA (in the past 3 months)
History of diabetes defined by diagnosis in Problems List in medical record
History of pancreatitis
History of gastroparesis
Gallbladder disease (in the past 3 months)
History of medullary thyroid carcinoma
Family history of medullary thyroid carcinoma
History of multiple endocrine neoplasia syndrome type 2
Family history of multiple endocrine neoplasia syndrome type 2
Cognitive inability to consent
Barrier to speaking, hearing, reading, or writing English
Pregnant or breastfeeding, or planning to become pregnant in the next 6 months
Too ill to complete study procedures

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Nashville?

Yes, this clinical trial (NCT07221214) has an active research site in Nashville, TN that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

HIV Treatment Options in Nashville, TN

If you're searching for hiv treatment options in Nashville, TN, this clinical trial (NCT07221214) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Nashville research site is actively enrolling participants for this clinical trial. You'll receive care from experienced hiv specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all hiv clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Nashville, TN