NCT06741618 · Columbia University
MyPEEPS Mobile Plus: A Multi-Level HIV Prevention Intervention for Young MSM
What this study is about
MyPEEPS Mobile Plus, a multi-level intervention for improving HIV prevention outcomes in YMSM, is a novel and evidence-driven approach using mobile technology to deliver HIV prevention information specifically developed for YMSM.
View original scientific description
MyPEEPS Mobile Plus, a multi-level intervention for improving HIV prevention outcomes in YMSM, is a novel and evidence-driven approach using mobile technology to deliver HIV prevention information specifically developed for YMSM. Building on strong preliminary work, the proposed research is the next logical step in a body of work designed to assess whether refinement of this mobile intervention used in combination with virtual PrEP Peer Navigation will result in improvements in PrEP uptake and a reduction in HIV-related behavior. This is key to advancing HIV prevention among HIV-negative US persons at extremely high-risk for HIV seroconversion.
Interventions
BEHAVIORAL
MyPEEPS Mobile
An evidence-based, digitally delivered mHealth sexual risk reduction intervention on HIV incidence
BEHAVIORAL
Electronic PrEP peer navigation
Electronic peer navigation to PreP services
Primary outcome measures
PrEP Initiation:
Time frame: Baseline, 6-month follow-up, 12-month follow-up
Participants will self-report attending at least one PrEP-related care visit to asess medical eligibility for PrEP initiation.
Who can participate
This study lists these criteria on ClinicalTrials.gov. A study coordinator reviews eligibility during screening — this page does not determine whether you qualify.
Inclusion criteria
- 16-25 years of age
- identify as male or non-binary
- male sex assigned at birth
- understand and read English
- own a smartphone
- report condomless anal sex with a male in the past year
- HIV-negative (OraQuick verified)
Exclusion criteria
- HIV Positive
- If study staff determine participant unable to consent due to obvious and severe cognitive impairment or under the influence of drugs or alcohol
- currently report consistent use of PrEP
- currently enrolled in another HIV prevention study
Where
- New York, New York
Collaborators
Ann & Robert H Lurie Children's Hospital of Chicago, Callen-Lorde Community Health Center, National Institute on Minority Health and Health Disparities (NIMHD)
Related conditions & keywords
Frequently asked questions
What is a clinical trial?
A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.
Is it safe to participate?
Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.
Will I be compensated?
Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.
Will I receive a placebo instead of treatment?
When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.
Can I leave a trial if I change my mind?
Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.
How long does a clinical trial last?
Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.
Data: ClinicalTrials.gov · synced Jun 26, 2026 · Source of record for eligibility and locations