Boston, MANCT07054073Now EnrollingIRB Ready

Hypertrophic Cardiomyopathy (HCM) Clinical Trial in Boston, MA

Access cutting-edge hypertrophic cardiomyopathy (hcm) treatment through this clinical trial at a research site in Boston. Study-provided care at no cost to qualified participants.

Sponsored by Christopher Kramer

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Expert Care in Boston

Access hypertrophic cardiomyopathy (hcm) specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related hypertrophic cardiomyopathy (hcm) treatment provided free

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Check if you qualify for this hypertrophic cardiomyopathy (hcm) clinical trial in Boston, MA

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Why Participate?

  • No-Cost Study Care

  • Local to Boston

    Convenient for MA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Boston site if eligible
  4. 4Begin participation

About This Hypertrophic Cardiomyopathy (HCM) Study in Boston

This study aims to learn what might predict heart problems (like sudden death from a fast heart rhythm or heart failure) in people with a genetic condition called hypertrophic cardiomyopathy (HCM). HCM causes the heart muscle to become thick, which can make the heart stiff and harder to work properly. It can also affect the heart's electrical system. This study is looking to enroll patients that were previously part of a research project called "HCMR - Novel Predictors of Outcome in Hypertrophic Cardiomyopathy." The results of that study are still being reviewed, but they might show that people who had a substance called Gadolinium (MRI contrast or dye) collected in their heart muscle may have a higher risk for heart problems, including sudden cardiac death. This is called "late gadolinium enhancement" (LGE). This study is aiming to do follow-up imaging on those patients to better understand how LGE affects people with HCM.

Sponsor: Christopher Kramer

Who Can Participate

Inclusion Criteria

Patients in the original HCMR cohort with:
Obstructive HCM
Males and females between 18 and 65 years of age
BMI \< 35 kg/m2
LVOT-G at entry as follows: Resting gradient ≥50 mmHg OR Resting gradient ≥30 mmHg and \<50 mmHg with post-Valsalva LVOT-G ≥50 mmHg • NYHA Class II or III or
Non-obstructive HCM
Same criteria as above except resting LVOT-G is \<30mmHg and post-Valsalva gradient \<50mm Hg
BMI \<40kg/m2
Elevated NT-proBNP \> 300 pg/mL at the time of enrollment

Exclusion Criteria

Paroxysmal atrial fibrillation or flutter documented prior to entry.
Paroxysmal or permanent atrial fibrillation requiring rhythm restoring treatment (eg, direct-current cardioversion, ablation procedure, or antiarrhythmic therapy) ≤6 months prior to entry. (This exclusion does not apply if atrial fibrillation has been treated with anticoagulation and adequately rate-controlled for \>6 months.)
History of syncope or sustained ventricular tachyarrhythmia with exercise within 6 months prior to entry.
Pregnancy due to potential risk of gadolinium to the fetus
Patients with a pacemaker that are pacer-dependent as they cannot undergo MRI

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Boston?

Yes, this clinical trial (NCT07054073) has an active research site in Boston, MA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Hypertrophic Cardiomyopathy (HCM) Treatment Options in Boston, MA

If you're searching for hypertrophic cardiomyopathy (hcm) treatment options in Boston, MA, this clinical trial (NCT07054073) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Boston research site is actively enrolling participants for this clinical trial. You'll receive care from experienced hypertrophic cardiomyopathy (hcm) specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all hypertrophic cardiomyopathy (hcm) clinical trials near you to find additional studies recruiting in your area.

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