Is NCT07082478 recruiting in Boston, MA?

Yes, NCT07082478 is currently recruiting participants at its Boston, MA location. This hypoglycemia clinical trial is actively enrolling qualified participants.

How do I join the hypoglycemia clinical trial in Boston?

To join this clinical trial in Boston, complete the eligibility form on this page. A study coordinator will contact you to discuss next steps and determine if you qualify.

Is participation in this Boston clinical trial free?

Yes, all study-related care is provided at no cost to qualified participants. Many studies also offer compensation for time and travel expenses.

Hypoglycemia Clinical Trial in Boston, MA

About This Hypoglycemia Study in Boston

This is a pilot study (small-scale study) that aims to understand more about how blood flow changes in people who have low blood sugar after bariatric surgery (post-bariatric hypoglycemia) compared to those who have had surgery without hypoglycemia, those who have hypoglycemia without surgery, or those who do not experience low blood sugar. This study has two phases. This is the first phase, and the purpose is to test comfort and feasibility of a novel in-ear wearable device (Lumia Health) that measures blood flow changes to the head. Information from the study will help the investigators determine if the device is suitable to be used in the second phase of the study.

Sponsor: Joslin Diabetes Center

Who Can Participate

Inclusion Criteria

Age 18-70 years of age, inclusive at screening.

Individuals able to provide informed consent and follow all study procedures, including complete daily food, activity, and symptom diaries, and willingness to provide access to medical record review.

For healthy control group: individuals without a history of upper gastrointestinal surgery and without reported symptoms of hypoglycemia.

Individuals with access to personal iPhone running operating system 16 (iOS) or later versions (not feasible for Android platform users) and a password-protected home Wi-Fi network.

Exclusion Criteria

History of coronary artery disease or presence of 2 or more risk factors including diabetes, uncontrolled hypertension, uncontrolled hyperlipidemia, and active tobacco use.

History of myocardial infarction, unstable angina or revascularization within the past 6 months.

History of syncope (unrelated to hypoglycemia) or diagnosed cardiac arrhythmia.

Documented hypoglycemia occurring in the fasting state (\> 12 hours fast).

Concurrent administration of β-blocker therapy.

Vigorous physical activity within 24 hours prior to assessment.

Seizure disorder (other than with suspect or documented hypoglycemia).

Hematocrit \< 33% (women) or \<36% (men) within the past 6 months.

History of insulinoma.

Use of central nervous system-active medications, including: antidepressants, anxiolytics, antipsychotics, stimulants, antiepileptics, sedatives and opioids.

History of severe neurologic vascular disease (e.g. cerebrovascular disease/stroke).

History of previous diseases associated with dysautonomia (e.g. multiple system atrophy, multiple sclerosis, Parkinson's disease).

Impaired hepatic function (aspartate amino transaminase and/or alanine amino transaminase \>2x upper limit of normal range), as determined within the past 6 months.

Impaired renal function (serum creatinine \>1.5 mg/dL), as determined within the past 6 months.

Serious psychiatric or substance abuse disorders (e.g. alcohol, opioid, cocaine use disorder), as judged by the study investigator.

Non-consent or inability to comply with study procedures.

Current pregnancy and/ or lactation.

Vulnerable individuals (e.g., fetuses, children, prisoners) and those judged by the investigator to be unsuitable for the study.

Individuals wearing earrings or other jewelry in the left ear who are unable or unwilling to remove them for the duration of the study.

Unwillingness to wear study masked CGM for duration of study

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Boston?

Yes, this clinical trial (NCT07082478) has an active research site in Boston, MA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Hypoglycemia Treatment Options in Boston, MA

If you're searching for hypoglycemia treatment options in Boston, MA, this clinical trial (NCT07082478) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Boston research site is actively enrolling participants for this clinical trial. You'll receive care from experienced hypoglycemia specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all hypoglycemia clinical trials near you to find additional studies recruiting in your area.

Hypoglycemia Clinical Trial in Boston, MA

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