Salem, MANCT02290834Now EnrollingIRB Ready

Impaired Cognition Clinical Trial in Salem, MA

Access cutting-edge impaired cognition treatment through this clinical trial at a research site in Salem. Study-provided care at no cost to qualified participants.

Sponsored by Massachusetts General Hospital

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Expert Care in Salem

Access impaired cognition specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related impaired cognition treatment provided free

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Check if you qualify for this impaired cognition clinical trial in Salem, MA

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Salem

    Convenient for MA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Salem site if eligible
  4. 4Begin participation

About This Impaired Cognition Study in Salem

This research study evaluates the effect of chemotherapy on cognition (thinking) and the brain in people with breast cancer.

Sponsor: Massachusetts General Hospital

Who Can Participate

Inclusion Criteria

Breast cancer patients treated with chemotherapy- Group 1 (experimental group)
Participants must meet the following criteria on screening examination to be eligible to participate in the behavioral +/- imaging components of study
New diagnosis histologically confirmed invasive breast cancer
Treatment plan to include chemotherapy
Female subjects age ≥ 60 years.
Life expectancy ≥ 1 year
Karnofsky Performance Score (KPS) ≥ 80
Ability to understand and the willingness to sign a written informed consent document.
Non-treated breast cancer patient controls- Group 2 (control group)
Participants must meet the following criteria on screening examination to be eligible to participate in the behavioral +/- imaging components of study:
New diagnosis histologically confirmed invasive breast cancer
Treatment plan does not include chemotherapy
Age ≥ 60 years.
Life expectancy ≥ 1 year
Karnofsky Performance Score (KPS) ≥ 80
Ability to understand and the willingness to sign a written informed consent document.
Healthy control subjects- Group 3 (control group)
Participants must meet the following criteria on screening examination to be eligible to participate in the behavioral +/- imaging components of study:
Age ≥ 60 years.
Life expectancy ≥ 1 year
Karnofsky Performance Score (KPS) ≥ 80
Ability to understand and the willingness to sign a written informed consent document.
Participants with well-controlled vascular risk factors, such as treated hypertension, treated hyperlipidemia or well-controlled Type II diabetes (glucose levels \<250) may be included.
Serum Pregnancy Testing: STAT quantitative serum hCG pregnancy testing for all women of childbearing potential. Imaging will not start until and unless the test result returns negative.

Exclusion Criteria

Participants who exhibit any of the following conditions at screening will not be eligible for admission into the study:
Participants with clinical or radiographic evidence of metastatic CNS disease
Subjects with MMSE scores below 24
Active or history of major psychiatric disorders such as schizophrenia, schizoaffective disorder, major affective disorder in mid-life, or treatment with ECT (Mild depression that is well treated with stable dose of SSRI antidepressants may be allowed).
Substance abuse within the past 2 years
Huntington's disease, hydrocephalus or seizure disorder
In addition to exclusion criteria above, participants who exhibit any of the following conditions at screening will not be eligible for admission into imaging portion of the study:
Participants with contraindications to MRI (i.e., implanted metal including pacemakers, cerebral spinal fluid shunts, aneurysm clips, artificial heart valves, ear implants or metal/foreign objects in the eyes and those with a history of claustrophobia), injuries to the eyes with metal without X-ray documentation that metal was removed

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Salem?

Yes, this clinical trial (NCT02290834) has an active research site in Salem, MA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Impaired Cognition Treatment Options in Salem, MA

If you're searching for impaired cognition treatment options in Salem, MA, this clinical trial (NCT02290834) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Salem research site is actively enrolling participants for this clinical trial. You'll receive care from experienced impaired cognition specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all impaired cognition clinical trials near you to find additional studies recruiting in your area.

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