NCT07675681 · Arizona State University
REmote Virtual Inspiration: Vitality and Energy
(REVIVE)
What this study is about
REVIVE is a randomly assigned controlled trial designed to evaluate the effects of a remotely delivered seated Tai Chi/Qigong (TCQ) intervention on cardiometabolic health, stress, sleep, and psychological well-being among women with mobility impairments.
View original scientific description
REVIVE is a randomized controlled trial designed to evaluate the effects of a remotely delivered seated Tai Chi/Qigong (TCQ) intervention on cardiometabolic health, stress, sleep, and psychological well-being among women with mobility impairments. Women with mobility impairments experience higher rates of obesity, cardiometabolic disease, chronic stress, sleep disturbances, and mental health concerns compared with women without disabilities. Limited access to accessible physical activity programs and barriers to participation in traditional exercise interventions contribute to these health disparities. Tai Chi and Qigong are gentle mind-body practices that may improve physical and psychological health through movement, breathing, and mindfulness techniques and can be adapted for individuals with limited mobility. Participants will be randomized to either a seated Tai Chi/Qigong intervention or a health education video control condition. During the 12-week intervention phase, participants will receive daily video-based content delivered remotely. Participants assigned to the Tai Chi/Qigong group will engage in seated meditative movement practices, while participants assigned to the control group will receive health and wellness education videos unrelated to physical activity or nutrition behavior change. Outcomes will be assessed remotely at baseline, post-intervention, and follow-up. Primary outcomes include waist circumference and indicators of physiological stress regulation, including heart rate variability and salivary cortisol. Secondary outcomes include perceived stress, emotion regulation, depression, anxiety, emotional eating, sleep quality, and sleep disturbance. Additional measures collected through wearable technology, sleep diaries, questionnaires, and biological samples will be used to examine potential behavioral, psychological, and physiological mechanisms underlying intervention effects. The findings from this study will contribute to the development of accessible, scalable, and evidence-based health promotion interventions designed to improve cardiometabolic health and overall well-being among women with mobility impairments.
Who can participate
This study lists these criteria on ClinicalTrials.gov. A study coordinator reviews eligibility during screening — this page does not determine whether you qualify.
Inclusion criteria
- Self-identify as a woman.
- Age 35-64 years.
- Mobility impairment lasting at least 1 year.
- Regular use of a mobility aid (e.g., wheelchair, scooter, walker, cane, crutches, or other assistive device).
- Community dwelling.
- Able to demonstrate sufficient upper-extremity mobility to participate in seated Tai Chi/Qigong activities.
- Access to a smartphone, tablet, or computer with internet access.
- Willing to wear a study-provided wearable device and complete study assessments.
- Reside in the United States.
- Waist circumference ≥ 33 inches (84 cm).
- Perceived Stress Scale (PSS) score ≥ 15.
- Insomnia Severity Index (ISI) score ≥ 8.
- Emotional eating indicated by a score \< 3 on the Mindful Eating Questionnaire (MEQ) Emotional Response subscale.
- Able to understand written and spoken English.
- Able to provide informed consent.
- Able to provide healthcare provider approval for participation.
Exclusion criteria
- Medical conditions that would make participation unsafe, as determined during screening.
- Inability to safely perform seated upper-body movements.
- Current participation in a structured Tai Chi, Qigong, or similar meditative movement program.
- Pregnancy, lactation, or plans to become pregnant during the study period.
- Cognitive, visual, auditory, or other impairments that would preclude completion of study procedures.
- Implanted cardiac devices or implanted electronic devices that interfere with physiologic measurements.
- Severe arrhythmia, left ventricular assist device (LVAD), or other conditions that interfere with heart rate variability assessment.
- Use of sleep medications three or more times per week.
- Medical conditions or medications that substantially affect autonomic nervous system activity, sleep, or stress-related outcomes.
- Uncontrolled cardiovascular, neurological, psychiatric, or other serious medical conditions that would preclude safe participation.
Where
- Phoenix, Arizona
Frequently asked questions
What is a clinical trial?
A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.
Is it safe to participate?
Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.
Will I be compensated?
Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.
Will I receive a placebo instead of treatment?
When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.
Can I leave a trial if I change my mind?
Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.
How long does a clinical trial last?
Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.
Data: ClinicalTrials.gov · synced Jul 6, 2026 · Source of record for eligibility and locations