NCT07299474 · Cedars-Sinai Medical Center
Efficacy of Lavender Aromatherapy on Anxiety and Pain Reduction During Awake Otolaryngologic Procedures
What this study is about
The purpose of this study is to evaluate the effectiveness of lavender aromatherapy in adult patients undergoing awake otolaryngologic procedures in the outpatient clinic setting.
View original scientific description
The purpose of this study is to evaluate the efficacy of lavender aromatherapy in adult patients undergoing awake otolaryngologic procedures in the outpatient clinic setting.
Interventions
OTHER
Lavender Aromatherapy
Lavender essential oil on cotton ball, and in aromatherapy diffuser
OTHER
Placebo Aromatherapy
Saline on cotton ball and in aromatherapy diffuser
Primary outcome measures
Change in visual analog scale anxiety, measured on a 10 cm scale
Time frame: Baseline, Periprocedural and Immediately after the procedure
A 10 cm visual analog scale is widely utilized to measure procedural anxiety, rated from 0 to 10, with 10 being the highest level of anxiety. The patient will provide a vertical mark above their level of anxiety. This number measured in mm (0-100) will be recorded both immediately before the procedure, and after the procedure, where the patient will record their average level of anxiety during the procedure. The change between pre-procedure, and post-procedure, will be recorded for each patient and compared between the lavender aromatherapy and placebo groups. The mean and median pre-procedure and post-procedure values will also be compared between the groups.
Likert scale of pain, measured on a scale of 0-10
Time frame: Immediately after the procedure
Patients will be asked to rate their your average level of pain on a scale of 0 (no pain) to 10 (worst possible pain) on a post-procedural questionnaire
Likert scale subjective improvement with pain, measured on scale of 1-5
Time frame: Immediately after the procedure
Patients will be asked in post-procedural questionnaire if they felt the aromatherapy helped with pain during the procedure, on a scale of 1 (strongly disagree) to 5 (strongly agree)
Who can participate
This study lists these criteria on ClinicalTrials.gov. A study coordinator reviews eligibility during screening — this page does not determine whether you qualify.
Inclusion criteria
- Adults ≥18 years old undergoing awake otolaryngologic procedures in the outpatient clinic
- Able to provide informed consent
Exclusion criteria
- Hypersensitivity to fragrances
- Taking systemic NSAIDs or other systemic pain-relieving medications within 48 hours
- Taking anxiolytics, hypnotics, sedating antihistamines, antidepressants on regular basis within 4 weeks
- Pregnant or breastfeeding
- Participation in another clinical research study within the prior 30 days
Where
- Los Angeles, California
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Frequently asked questions
What is a clinical trial?
A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.
Is it safe to participate?
Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.
Will I be compensated?
Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.
Will I receive a placebo instead of treatment?
When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.
Can I leave a trial if I change my mind?
Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.
How long does a clinical trial last?
Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.
Data: ClinicalTrials.gov · synced Dec 23, 2025 · Source of record for eligibility and locations