NCT07148999 · Urmila DIwekar
An Advanced Decision Support Tool for Personalized Medicine for IVF Using Modeling and Optimization for Provera
What this study is about
A clinical trial will determine the effectiveness of using the Opt-IVF decision support tool for each patient's personalized and optimal drug dosage profile in the United States.
View original scientific description
A clinical trial will determine the effectiveness of using the Opt-IVF decision support tool for each patient's personalized and optimal drug dosage profile in the United States.
Interventions
COMBINATION_PRODUCT
Opt-IVF
Opt-IVF provides optimized dosage profile for each patient
OTHER
Control
Physicians will decide the dosage for each day for patients
Primary outcome measures
Total Gonadotropin Dosage
Time frame: Two weeks after the start of the cycle
Total Gonadotropin Dosage for the cycle
Total Oocytes Retrieved
Time frame: Two weeks after the start of the stimulation cycle
Total Oocytes Retrieved
M2 Oocytes
Time frame: Two weeks after the start of the stimulation cycle
Total M2 Oocytes
Total Embryos Formed
Time frame: Two weeks after the start of stimulation cycle
Total Embryos Formed
Grade A embryos/Blastocytes
Time frame: Three weeks after the start of stimulation cycle
Grade A Day 3 Embryos or Grade A Day 5 Blastocytes
Who can participate
This study lists these criteria on ClinicalTrials.gov. A study coordinator reviews eligibility during screening — this page does not determine whether you qualify.
Inclusion criteria
- infertile women
Exclusion criteria
- All female patients who will not undergo IVF or whose cycles will be converted to IUI. Male patients will not be enrolled in this study. No donor cycles.
Where
- Houston, Texas
- San Antonio, Texas
Collaborators
IVF Academy of USA, Positivf Fertility
Related conditions & keywords
Frequently asked questions
What is a clinical trial?
A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.
Is it safe to participate?
Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.
Will I be compensated?
Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.
Will I receive a placebo instead of treatment?
When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.
Can I leave a trial if I change my mind?
Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.
How long does a clinical trial last?
Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.
Data: ClinicalTrials.gov · synced Sep 29, 2025 · Source of record for eligibility and locations