Durham, NCNCT06038630Now EnrollingIRB Ready

Interstitial Lung Disease Clinical Trial in Durham, NC

Access cutting-edge interstitial lung disease treatment through this phase 2 clinical trial at a research site in Durham. Study-provided care at no cost to qualified participants.

Sponsored by Bastiaan Driehuys

Quick Self-Assessment

See if you qualify for this Durham location

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Expert Care in Durham

Access interstitial lung disease specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related interstitial lung disease treatment provided free

Apply for This Durham Location

Check if you qualify for this interstitial lung disease clinical trial in Durham, NC

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Durham

    Convenient for NC residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Durham site if eligible
  4. 4Begin participation

About This Interstitial Lung Disease Study in Durham

The goal of this NIH-sponsored study is to characterize three biomarkers derived from 129Xe gas exchange MRI and to understand how they change in response to interventions.

Sponsor: Bastiaan Driehuys

Who Can Participate

Inclusion Criteria

for Healthy Volunteers: (Inclusion Criteria: Subjects must meet all of the following inclusion criteria to be eligible for enrollment into the trial)
Outpatients of either gender, age \> 18
Willing and able to give informed consent and adhere to visit/protocol (Consent must be given before any study procedures are performed.)
Subject has no diagnosed pulmonary conditions
Subject has not smoked in the previous 5 years
Smoking history, if any, is less than or equal to 5 pack-years
No history of using other inhaled products more than 1/week for \> 1 year Inclusion Criteria for Transfusion and Phlebotomy Patients:
In-patient or outpatients of either sex, age \> 18
Willing and able to give informed consent and adhere to visit/protocol And one of the following:
Patients who are scheduled to receive a red cell transfusion for anemia.
Patients who are scheduled to undergo therapeutic phlebotomy to treat erythrocytosis or polycythemia
Healthy volunteers undergoing voluntary whole blood donation (healthy volunteer inclusion criteria noted above) Inclusion Criteria for Oxygen Administration Patients:
In-patient or outpatients of either sex, age \> 18
Willing and able to give informed consent and adhere to visit/protocol And one of the following categories (ILD, Dyspnea, CTEPH, or Healthy):
Interstitial Lung Disease or Dyspnea
Physician diagnosis of Interstitial Lung Disease by a pulmonologist using established criteria or physician referral of patient with dyspnea OR
Chronic Thromboembolic Pulmonary Hypertension (CTEPH)
Patients with a diagnosis of CTEPH, defined as mean PA pressure \>20 mmHg with a pulmonary vascular resistance \>2 WU and pulmonary capillary wedge pressure ≤15 mmHg at right heart catheterization with evidence of chronic thromboembolic disease on clinical imaging after 3 months of anticoagulation
Scheduled for pulmonary thromboendoarterectomy (PTE) surgery and willing to re-turn 3-6 months after for optional follow-up scans OR
Healthy Volunteer (criteria noted above) Inclusion Criteria for Acute or Chronic Pulmonary Embolism Patients:
In-patient or outpatients of either sex, age \> 18
Willing and able to give informed consent and adhere to visit/protocol And one of the following categories (Acute or Chronic)
Acute Pulmonary Embolism
Patients presenting with acute PE 24-48hrs post-admission
Willing to return after 3-6 months of anti-coagulation therapy OR
Chronic Thromboembolic Pulmonary Hypertension (CTEPH)
Patients with a diagnosis of CTEPH, defined as mean PA pressure \>20 mmHg with a pulmonary vascular resistance \>2 WU and pulmonary capillary wedge pressure ≤15 mmHg at right heart catheterization with evidence of chronic thromboembolic disease on clinical imaging after 3 months of anticoagulation
Scheduled for pulmonary thromboendoarterectomy (PTE) surgery and willing to re-turn 3-6 months after for optional follow-up scans

Exclusion Criteria

for All subjects: Subjects presenting with any of the following will not be included in the trial:
MRI is contraindicated based on responses to MRI screening questionnaire
Subject is pregnant or lactating
Resting O2 saturation \<90% with maximum supplemental O2 delivered by nasal canula
Respiratory illness of a bacterial or viral etiology within 30 days of MRI
Subject has history of any known ventricular cardiac arrhythmia
Subject has history of cardiac arrest within the last year
Subject does not fit into 129Xe vest coil used for MRI
Subject cannot hold his/her breath for 10 seconds
Subject deemed unlikely to be able to comply with instructions during imaging
Medical or psychological conditions which, in the opinion of the investigator, might create undue risk to the subject or interfere with the subject's ability to comply with the protocol requirements

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Durham?

Yes, this clinical trial (NCT06038630) has an active research site in Durham, NC that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Interstitial Lung Disease Treatment Options in Durham, NC

If you're searching for interstitial lung disease treatment options in Durham, NC, this clinical trial (NCT06038630) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Durham research site is actively enrolling participants for this phase 2 clinical trial. You'll receive care from experienced interstitial lung disease specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all interstitial lung disease clinical trials near you to find additional studies recruiting in your area.

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