Chicago, ILNCT06925321Now EnrollingIRB Ready

Invasive Mold Infections Clinical Trial in Chicago, IL

Access cutting-edge invasive mold infections treatment through this clinical trial at a research site in Chicago. Study-provided care at no cost to qualified participants.

Sponsored by Basilea Pharmaceutica

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Expert Care in Chicago

Access invasive mold infections specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related invasive mold infections treatment provided free

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Check if you qualify for this invasive mold infections clinical trial in Chicago, IL

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Why Participate?

  • No-Cost Study Care

  • Local to Chicago

    Convenient for IL residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Chicago site if eligible
  4. 4Begin participation

About This Invasive Mold Infections Study in Chicago

The purpose of this study is to evaluate the efficacy and safety of fosmanogepix (administered IV or oral) for the treatment of adult patients with invasive mold infections. The study is looking for patients who have been diagnosed with invasive mold infections. The maximum study duration will be approximately 8 months, including a target study treatment duration of 84 days which can be extended up to 180 days and follow-up period. The patient will be assigned to one of two treatment cohorts: Cohort A (primary therapy): Patients will receive either the study drug or institutional standard of care antifungal treatment. Cohort B (salvage treatment; i.e. treatment given after patients did not respond to previous treatments or did not tolerate them): Patients will receive the study drug The primary aim is to compare the all cause mortality with a fixed threshold at Day 42.

Sponsor: Basilea Pharmaceutica

Who Can Participate

Inclusion Criteria

Diagnosis of proven or probable Invasive mold infection (IMI) defined in accordance with the Revision and Update of the Consensus Definitions of Invasive Fungal Disease from the EORTC/MSGERC as adapted for this study and caused by Aspergillus spp. (in patients with limited treatment options), Fusarium spp., Lomentospora prolificans, Mucorales fungi, or other multi-drug resistant molds.
Patient's condition allows for appropriate infection source control measures. Main

Exclusion Criteria

Refractory hematologic malignancy.
Chronic aspergillosis, aspergilloma, or allergic bronchopulmonary aspergillosis.
Coronavirus disease 2019 (COVID-19) associated mucormycosis.
Invasive fungal disease caused by more than one fungal pathogen is not permitted in Cohort A but is permitted in Cohort B.
Patients with a Karnofsky Performance Status \< 20 at Screening.
Requirement, or anticipated requirement, for hemodialysis, peritoneal dialysis, or hemofiltration.
Patients with known human immunodeficiency virus infection.
Ongoing neurological disorders.
Patients receiving hospice/comfort care only.
Other medical or psychiatric condition.
Current use of any prohibited concomitant medication(s).
Current/ previous administration of an investigational drug within 30 days.
Prior enrollment in this or any previous study of fosmanogepix.
Moderate or severe hepatic impairment.
Patient who is pregnant or lactating.
Known hypersensitivity to fosmanogepix, manogepix, or any of their excipients.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Chicago?

Yes, this clinical trial (NCT06925321) has an active research site in Chicago, IL that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Invasive Mold Infections Treatment Options in Chicago, IL

If you're searching for invasive mold infections treatment options in Chicago, IL, this clinical trial (NCT06925321) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Chicago research site is actively enrolling participants for this clinical trial. You'll receive care from experienced invasive mold infections specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all invasive mold infections clinical trials near you to find additional studies recruiting in your area.

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