Palo Alto, CANCT05241444Now EnrollingIRB Ready

IPEX Clinical Trial in Palo Alto, CA

Access cutting-edge ipex treatment through this phase 1 clinical trial at a research site in Palo Alto. Study-provided care at no cost to qualified participants.

Sponsored by Bacchetta, Rosa, MD

Quick Self-Assessment

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Expert Care in Palo Alto

Access ipex specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related ipex treatment provided free

Apply for This Palo Alto Location

Check if you qualify for this ipex clinical trial in Palo Alto, CA

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Palo Alto

    Convenient for CA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Palo Alto site if eligible
  4. 4Begin participation

About This IPEX Study in Palo Alto

This first-in-human, Phase 1 clinical trial will test the feasibility of the manufacturing and the safety of the administration of CD4\^LVFOXP3 in up to 30 evaluable human participants with IPEX and evaluate the impact of the CD4\^LVFOXP3 infusion on the disease.

Sponsor: Bacchetta, Rosa, MD

Who Can Participate

Inclusion Criteria

Body weight greater than 8 kg, unless assessed as able to tolerate leukapheresis
FOXP3 gene mutation
Medical history of progressive symptoms of IPEX with persistency of some symptoms and/or signs requiring immune suppressive medication. The participant may or may not be on immunosuppression at time of starting the study.
Uncontrolled IPEX disease but unable to tolerate immune suppressive medication
Recurrent IPEX symptoms, requiring immune suppressive medications, in participants who have had prior allogeneic (allo) blood stem cell transplantation (HSCT).
≥ 50% Performance rating on Lansky/Karnofsky Scale
Organ and marrow function within acceptable levels of function
Absence of ongoing infections
Must be able to consent if an adult

Exclusion Criteria

Medical instability
Less than 6 months life expectancy
Inability to meet limits for steroid dosing
Eligible for an HLA matched sibling or matched unrelated donor blood stem cell transplant, and be willing to undergo transplant.
Unrelated or comorbid disease
Allergy to any study medication, product, or intervention
Currently receiving another experimental treatment
History of malignancy, unless disease free for at least 2 years, with the exception of non melanoma skin cancer or carcinoma in situ

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Palo Alto?

Yes, this clinical trial (NCT05241444) has an active research site in Palo Alto, CA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

IPEX Treatment Options in Palo Alto, CA

If you're searching for ipex treatment options in Palo Alto, CA, this clinical trial (NCT05241444) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Palo Alto research site is actively enrolling participants for this phase 1 clinical trial. You'll receive care from experienced ipex specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all ipex clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Palo Alto, CA