Guntersville, ALNCT07519395Now EnrollingIRB Ready

Irritable Bowel Syndrome Clinical Trial in Guntersville, AL

Access cutting-edge irritable bowel syndrome treatment through this clinical trial at a research site in Guntersville. Study-provided care at no cost to qualified participants.

Sponsored by GlaxoSmithKline

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Expert Care in Guntersville

Access irritable bowel syndrome specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related irritable bowel syndrome treatment provided free

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Check if you qualify for this irritable bowel syndrome clinical trial in Guntersville, AL

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Guntersville

    Convenient for AL residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Guntersville site if eligible
  4. 4Begin participation

About This Irritable Bowel Syndrome Study in Guntersville

This study is designed to evaluate the efficacy and safety of camlipixant in adults with IBS-D and IBS-M. The study has two parts. After the first part, some participants will be randomly chosen again to either get a higher dose or stop the drug.

Sponsor: GlaxoSmithKline

Who Can Participate

Inclusion Criteria

Male or female aged 18 to 80 years inclusive, at the time of signing the Informed consent form (ICF).
Diagnosis of IBS-D or IBS-M according to the Rome IV criteria at screening
Moderate or severe irritable bowel syndrome (IBS) based on Irritable bowel syndrome Severity Scoring System (IBS SSS) at screening visit
Weekly API score \>=4.0 in each week of the run-in period
IBS-D: at least one stool with BSFS Type 6 or 7 consistency on at least 2 days in each week of the run-in period
IBS-M: an average of 2 days per week with abnormal bowel movements (BSFS Type 1, 2, 6, or 7) during the run-in period, and greater than (\>)25% of abnormal bowel movements must be Type 6 or 7 and \>25% Type 1 or 2

Exclusion Criteria

Diagnosis of Irritable bowel syndrome - constipation (IBS-C) or Irritable bowel syndrome - unclassified (IBS-U)
History or presence of inflammatory or immune-mediated Gastrointestinal (GI) disorders e.g. inflammatory bowel disease, microscopic colitis, or celiac disease
History or presence of GI infection (confirmed with stool culture) within 3 months prior to screening
History or presence of bile salt diarrhea
History of a primary psychiatric diagnosis that the Investigator considers may interfere with study assessments (e.g., schizophrenia, schizoaffective disorder, major depression, anxiety, panic attacks or bipolar disorder) OR Hospital Anxiety and Depression Scale (HADS) score of \>10 at screening.
Prior use of more than two of the following therapies or classes of therapy for the management of IBS:
Antidepressants or neuromodulators (e.g., Tricyclic antidepressant \[TCAs\], Selective serotonin reuptake inhibitor \[SSRIs\], gabapentinoids)
Antibiotics (e.g., rifaximin, neomycin)
5-hydroxytryptamine 3 (5-HT3) receptor antagonists (e.g., alosetron, ramosetron, ondansetron)
Mu-opioid receptor agonists (e.g., eluxadoline)
Secretagogues (e.g., linaclotide, lubiprostone, plecanatide, tenapanor)
5-hydroxytryptamine 4 (5-HT4) receptor agonists (e.g., tegaserod)
Abnormal thyroid function tests less than (\<) Lower limit of normal (LLN) or greater than (\>) upper limit of normal (ULN) confirmed at screening with Thyroid stimulating hormone (TSH)
Positive celiac serology
Elevated fecal calprotectin levels
QT interval corrected using Fridericia's formula (QTcF) \>450 millisecond (msec) or QTcF \>480 msec for participants with bundle branch block using the Fridericia's corrected QT interval.
Clinically significant abnormal laboratory tests at screening, after one repeat laboratory test if allowed by the Medical Monitor, including the following:
Alanine aminotransferase (ALT) \>2\*ULN
Total Bilirubin \>1.5\*ULN
Aspartate aminotransferase (AST) \>2\*ULN
Current or chronic history of liver disease (Child-Pugh class A, B, or C) or biliary abnormalities (with the exception of asymptomatic gallstones). Participants with known or suspected Gilbert's Syndrome are not permissible.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Guntersville?

Yes, this clinical trial (NCT07519395) has an active research site in Guntersville, AL that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Irritable Bowel Syndrome Treatment Options in Guntersville, AL

If you're searching for irritable bowel syndrome treatment options in Guntersville, AL, this clinical trial (NCT07519395) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Guntersville research site is actively enrolling participants for this clinical trial. You'll receive care from experienced irritable bowel syndrome specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all irritable bowel syndrome clinical trials near you to find additional studies recruiting in your area.

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