Durham, NCNCT06639984Now EnrollingIRB Ready

Irritable Bowel Syndrome Clinical Trial in Durham, NC

Access cutting-edge irritable bowel syndrome treatment through this clinical trial at a research site in Durham. Study-provided care at no cost to qualified participants.

Sponsored by Dr Bruno Chumpitazi, M.D.

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Expert Care in Durham

Access irritable bowel syndrome specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related irritable bowel syndrome treatment provided free

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Check if you qualify for this irritable bowel syndrome clinical trial in Durham, NC

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Durham

    Convenient for NC residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Durham site if eligible
  4. 4Begin participation

About This Irritable Bowel Syndrome Study in Durham

The goal of this clinical trial is to learn if a fiber (psyllium) can change the way bacteria use fructans (a type of sugar) and whether psyllium can help decrease childhood irritable bowel syndrome (IBS) symptoms when eating fructans. The main questions it aims to answer are: Aim 1: The effect of psyllium at two doses given with a fructan meal on microbial fructan fermentation (intracolonic pH; H2 gas production; gut microbiome composition; fecal short-chain fatty acids, lactate, glycomics). Aim 2: Determine the impact of psyllium given with a fructan meal on fructan-induced GI symptoms. Participants will first be asked to eat a specific diet over two three-day periods to determine if fructans worsen their IBS symptoms. Those with worsening symptoms with fructans will be asked to participate in the second part of the study. This includes two weeks of baseline (no change in diet) and two weeks of eating a specific diet with fructans with either psyllium or glucose. Participants will be asked to complete pain and stool diaries, submit stool specimens, swallow a pill to capture gut acid levels, and give breath samples.

Sponsor: Dr Bruno Chumpitazi, M.D.

Who Can Participate

Inclusion Criteria

Children between the ages of 12-17 years meeting pediatric Rome IV criteria for IBS

Exclusion Criteria

Children who have had previous bowel surgery, have documented GI disorders (e.g., ulcerative colitis), or a serious chronic medical condition (e.g., diabetes)
weight and/or height are \> or \< 2 SD for age
have chronic conditions with GI symptoms (e.g., cystic fibrosis)
have been on antibiotics or probiotics within 3 months (because of potential alterations to the GI microbiome0
girls who are pregnant (tested with urine beta-human chorionic gonadotropin at the initial visit)

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Durham?

Yes, this clinical trial (NCT06639984) has an active research site in Durham, NC that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Irritable Bowel Syndrome Treatment Options in Durham, NC

If you're searching for irritable bowel syndrome treatment options in Durham, NC, this clinical trial (NCT06639984) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Durham research site is actively enrolling participants for this clinical trial. You'll receive care from experienced irritable bowel syndrome specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all irritable bowel syndrome clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Durham, NC