Miami, FLNCT06289985Now EnrollingIRB Ready

Ischemic Stroke Clinical Trial in Miami, FL

Access cutting-edge ischemic stroke treatment through this clinical trial at a research site in Miami. Study-provided care at no cost to qualified participants.

Sponsored by Medical University of South Carolina

Quick Self-Assessment

See if you qualify for this Miami location

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Expert Care in Miami

Access ischemic stroke specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related ischemic stroke treatment provided free

Apply for This Miami Location

Check if you qualify for this ischemic stroke clinical trial in Miami, FL

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Why Participate?

  • No-Cost Study Care

  • Local to Miami

    Convenient for FL residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Miami site if eligible
  4. 4Begin participation

About This Ischemic Stroke Study in Miami

STEP is a Randomized, Multifactorial, Adaptive Platform trial that seeks to optimize the care of patients with acute ischemic stroke (AIS) due to large (LVO) or medium vessel occlusions (MVO).

Sponsor: Medical University of South Carolina

Who Can Participate

Inclusion Criteria

Suspected diagnosis acute ischemic stroke
Likely causative intracranial large or medium vessel occlusion STEP PLATFORM

Exclusion Criteria

Proven contraindication to endovascular thrombectomy
Prisoners/incarcerated DOMAIN-SPECIFIC ELIGIBILITY CRITERIA: Each domain may have additional eligibility criteria. STEP EVT INDICATION EXPANSION DOMAIN INCLUSION CRITERIA: 1\. Age 18 years or older 2. Pre-stroke modified Rankin Scale score 0-2 3. Presentation to enrolling hospital within 24 hours of last known well/stroke onset 4. Able to initiate arterial puncture within 2 hours from qualifying CTA/MRA or CTP/MRP imaging \*CT/MR and qualifying CTA/MRA or CTP/MRP should be repeated if more than 120 minutes have elapsed since the imaging and randomization has not been performed. The exception is for LVO Mild deficit/Low NIHSS 0-5 for which imaging would only need to be repeated if there has been significant improvement in the NIHSS prior to randomization. 5\. Has one of the following presentations:
LVO patients with mild deficits/low NIHSS (must have both):
Mild presenting neurologic deficits - NIHSS 0-5 (Must have some focal neurological deficit attributable to the target occlusion if NIHSS 0)
Complete occlusion of the intracranial Internal Carotid Artery (ICA) or M1 Middle Cerebral Artery (MCA)
Medium/Distal Vessel Occlusion:
Visualized complete occlusion or perfusion deficit (Tmax \> 4s) supportive of a cortical branch occlusion in one of the following vessels: i) Non-dominant/Co-dominant M2 (defined as serving \< 50% of entire overall MCA territory) ii) M3
If symptom onset is \> 6h, the core must be less than 50% of the territory supplied by the occluded vessel as evident by either: i) Hypodensity and loss of grey-white border on NCCT or ii)ADC \<620 mm2/s on diffusion MRI or rCBF\<30% on CTP
NIHSS \> =8 STEP EVT INDICATION EXPANSION DOMAIN EXCLUSION CRITERIA:
Presumed septic embolus; suspicion of bacterial endocarditis
Seizure at stroke onset or between onset and enrollment
Known anaphylactic reaction to contrast material that precludes endovascular reperfusion therapy
Intracranial occlusion suspected to be chronic, based on history and/or imaging
Intracranial dissection, based on history and/or imaging
Cerebral vasculitis, based on history and/or imaging
Known pregnancy
Known pre-existing medical, neurological or psychiatric disease that would confound the neurological or functional evaluations
Known serious, advanced, or terminal illness or life expectancy less than 6 months in the investigator judgment
Known or high suspicion for underlying intracranial atherosclerotic disease (ICAD)
Laboratory a. Known platelet count \<100,000/uL
CT ASPECT score \<6 (MRI ASPECT score \<7)
Unfavorable vascular anatomy that limits access to the occluded artery precluding endovascular reperfusion therapy.
Acute occlusions in multiple vascular territories (e.g., bilateral anterior circulation, or anterior/posterior circulation)
Tandem occlusions
Significant mass effect with midline shift (\>5mm)
Evidence of intra-cranial tumor (except small meningioma defined as (1) \<=3 cm, (2) asymptomatic) as confirmed on CT/MRI)
Evidence of acute intracranial hemorrhage

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Miami?

Yes, this clinical trial (NCT06289985) has an active research site in Miami, FL that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Ischemic Stroke Treatment Options in Miami, FL

If you're searching for ischemic stroke treatment options in Miami, FL, this clinical trial (NCT06289985) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Miami research site is actively enrolling participants for this clinical trial. You'll receive care from experienced ischemic stroke specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all ischemic stroke clinical trials near you to find additional studies recruiting in your area.

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