Aurora, CONCT07424352Now EnrollingIRB Ready

Knee Arthritis, Osteoarthritis Clinical Trial in Aurora, CO

Access cutting-edge knee arthritis, osteoarthritis treatment through this clinical trial at a research site in Aurora. Study-provided care at no cost to qualified participants.

Sponsored by University of Colorado, Denver

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Expert Care in Aurora

Access knee arthritis, osteoarthritis specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related knee arthritis, osteoarthritis treatment provided free

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Check if you qualify for this knee arthritis, osteoarthritis clinical trial in Aurora, CO

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Aurora

    Convenient for CO residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Aurora site if eligible
  4. 4Begin participation

About This Knee Arthritis, Osteoarthritis Study in Aurora

This study is testing whether a new type of exercise program, called eccentric overload training using a flywheel device, can improve stair-climbing ability in people with knee osteoarthritis. The flywheel device provides resistance throughout the entire movement and gives extra challenge during the muscle-lengthening phase of exercise. This type of training may improve muscle structure, strength, and coordination more effectively than conventional methods. The study's central idea is that better muscle quality and improved coordination will lead to smoother, safer stair movement and reduce the risk of falls. Advanced tools such as ultrasound imaging and motion analysis will be used to measure muscle health and movement patterns in detail. The hypothesis is that individuals with knee osteoarthritis have poorer muscle quality and less coordinated stair-stepping compared to healthy adults, and that performing eccentric overload training will enhance muscle quality, improve movement coordination, and make stair navigation safer and more efficient.

Sponsor: University of Colorado, Denver

Who Can Participate

Inclusion Criteria

Osteoarthritis (OA) Group:
Aged 40-70 years
Radiographically confirmed knee OA (Kellgren-Lawrence \[KL\] Grade 2 or 3)
Able to walk independently (assistive devices permitted) Inclusion Criteria Healthy Control Group:
Aged 40-70 years
No radiographic evidence of knee OA (KL Grade 0 or 1)
No frequent knee pain
No history of:
Knee surgery (e.g., ACL reconstruction, meniscectomy, patellar realignment)
Significant knee injury (e.g., ligament tears, fractures, dislocations)
Diagnosed knee conditions (e.g., patellofemoral pain syndrome, bursitis)

Exclusion Criteria

Uncontrolled hypertension or other cardiovascular disease
A musculoskeletal condition preventing physical testing
Neurological muscle weakness (e.g., stroke, spinal cord injury)
BMI \>34.9 kg/m²
Recent hospitalization (past 3 months)

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Aurora?

Yes, this clinical trial (NCT07424352) has an active research site in Aurora, CO that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Knee Arthritis, Osteoarthritis Treatment Options in Aurora, CO

If you're searching for knee arthritis, osteoarthritis treatment options in Aurora, CO, this clinical trial (NCT07424352) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Aurora research site is actively enrolling participants for this clinical trial. You'll receive care from experienced knee arthritis, osteoarthritis specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all knee arthritis, osteoarthritis clinical trials near you to find additional studies recruiting in your area.

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