Springfield, MANCT07674901Now EnrollingIRB Ready

Knee Arthritis, Osteoarthritis Clinical Trial in Springfield, MA

Access cutting-edge knee arthritis, osteoarthritis treatment through this clinical trial at a research site in Springfield. Study-provided care at no cost to qualified participants.

Sponsored by Margaret L Gourlay, MD, MPH

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Expert Care in Springfield

Access knee arthritis, osteoarthritis specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related knee arthritis, osteoarthritis treatment provided free

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Check if you qualify for this knee arthritis, osteoarthritis clinical trial in Springfield, MA

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Why Participate?

  • No-Cost Study Care

  • Local to Springfield

    Convenient for MA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Springfield site if eligible
  4. 4Begin participation

About This Knee Arthritis, Osteoarthritis Study in Springfield

The purpose of this superiority randomized controlled trial is to evaluate the effect of daily knee sleeve use on 5-year radiographic knee osteoarthritis progression and knee-related symptoms in older adults with chronic knee pain. The investigators will recruit 235 individuals aged 50-64 years at baseline with chronic (≥ 3 months) knee pain, randomized to daily use of an elasticized fabric knee sleeve versus no knee sleeve use. Participants will have knee radiographs at baseline and year 5 and will complete a survey including Knee injury and Osteoarthritis Outcome Score (KOOS) subscales for pain, knee function and quality of life at 3 months and annually. A prespecified interim analysis of the 1-year KOOS subscore data will be performed.

Sponsor: Margaret L Gourlay, MD, MPH

Who Can Participate

Inclusion Criteria

Aged 50-64 years at the time of his/her baseline eligibility screening
Unilateral or bilateral chronic (≥ 3 months) knee pain
Knee circumference between 12" (30 cm) and 22" (56 cm) measured over center of kneecap; or if a larger size is needed, thigh circumference up to 28" (71 cm) measured at 4" ABOVE center of knee cap per manufacturers' size specifications for the knee sleeves used in the intervention
English-speaking and able to provide informed consent for study participation

Exclusion Criteria

History of knee replacement surgery in the painful/affected knee(s)
Knee replacement surgery or arthroscopic procedure scheduled or anticipated in the affected knee(s) within 1 year after study eligibility screening
Self-reported history or medical documentation of rheumatoid arthritis, psoriatic arthritis or other inflammatory arthritis in any joint; peripheral arterial disease or other vascular or circulatory disorder; blood clotting disorder; bleeding disorder or self-reported easy bruising; current treatment with an anticoagulant or antiplatelet agent; immobility; nonambulatory status; knee ligament tear or rupture; or lower extremity fracture requiring internal or external fixation within 1 year before study eligibility screening
History of unprovoked falls
Current use of a rigid or hinged knee brace made of metal, plastic or fiberglass, or prescription for a knee brace for the affected knee(s)
Previous use of a knee sleeve/fabric knee support on the affected knee(s) for over 6 months cumulative time
Inability to pull on or remove elasticized knee sleeve from affected knee(s)
Kellgren-Lawrence (KL) grade 4 on a baseline standing/weightbearing A/P knee radiograph of the affected knee(s) is excluded because it is the highest KL grade, so a primary outcome event (transition to a higher grade) is impossible.
Moderate to severe knee effusion on baseline radiographs of the painful knee(s) is excluded due to the potential risk of harm and discomfort from the compressive effect of a knee sleeve. Individuals with moderate to severe knee effusion during the first screening assessment who are otherwise eligible will be invited to have a repeat A/P knee x-ray 2 months later to reassess radiological eligibility. If the effusion is mild or has resolved by that time, the individual will be invited to enroll in the study.
Pregnancy (because of x-ray exposure)
Cannot attend a 5-year study assessment for follow-up knee radiographs
Investigator discretion

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Springfield?

Yes, this clinical trial (NCT07674901) has an active research site in Springfield, MA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Knee Arthritis, Osteoarthritis Treatment Options in Springfield, MA

If you're searching for knee arthritis, osteoarthritis treatment options in Springfield, MA, this clinical trial (NCT07674901) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Springfield research site is actively enrolling participants for this clinical trial. You'll receive care from experienced knee arthritis, osteoarthritis specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all knee arthritis, osteoarthritis clinical trials near you to find additional studies recruiting in your area.

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