Cambridge, MANCT06686680Now EnrollingIRB Ready

Knee Osteoarthristis Clinical Trial in Cambridge, MA

Access cutting-edge knee osteoarthristis treatment through this clinical trial at a research site in Cambridge. Study-provided care at no cost to qualified participants.

Sponsored by Spaulding Rehabilitation Hospital

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Expert Care in Cambridge

Access knee osteoarthristis specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related knee osteoarthristis treatment provided free

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Check if you qualify for this knee osteoarthristis clinical trial in Cambridge, MA

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Cambridge

    Convenient for MA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Cambridge site if eligible
  4. 4Begin participation

About This Knee Osteoarthristis Study in Cambridge

This study is recruiting current or former athletes who had ACL reconstruction surgery over a year ago and have been diagnosed with knee osteoarthritis (OA). We are doing the research to investigate the effects of extracorporeal shockwave therapy (ESWT) on pain, function, biomechanics, knee range of motion and strength, inflammation, and joint structure and integrity of the knee.

Sponsor: Spaulding Rehabilitation Hospital

Who Can Participate

Inclusion Criteria

Previous ACL reconstruction using an autograft or allograft in the knee with PTOA
Minimum of one year following ACL reconstruction surgery
Between ages of 18 and 55
No clear contraindication to complete protocol including mechanical symptoms which would limit ability to complete the study
Score on KOOS for 2 of 4 domains (pain, symptoms, activities of daily living (ADL), quality of life (QOL)) of 85 or lower
Primary pain is coming from the knee
Diagnosis of PTOA based on clinical diagnosis and confirmation with radiographic evidence by a medical professional prior to study enrollment. If individuals have suspected OA based on impairments such as pain, they must have a score on KOOS for 2 of 4 domains (pain, symptoms, activities of daily living (ADL), quality of life (QOL)) of 85 or lower to participate in the study.

Exclusion Criteria

Have previously received injections to the knee joint within the past 3 months
Women who are pregnant or those who are planning to become pregnant. This is due to the fact that pregnancy will reduce participants activity after the treatment and the safety concerns related to shockwave treatment. - Participants with neuropathy affecting sensation to pain
Participants with a known underlying cardiac disease that could be affected by shockwave therapy
Chronic rheumatological conditions, immunodeficiency, severe asthma, connective tissue disorder (i.e. Ehlers-Danlos Syndrome), or other medical conditions (ex. active malignancy, severe asthma) outside of PTOA that are known to impact inflammatory state or requiring chronic use of oral or intravenous immune modulatory medications. Asthma requiring use of inhalers only is not an exclusion criteria
Neuropathy diagnosis that can affect response to pain
No active use of oral steroids or anti-inflammatories at the time of enrollment
Have bilateral ACL injury or reconstruction surgery, or have had ACL revision surgery
No active malignancy and at least five years in remission
Previous ESWT treatment using study treatment devices for management of knee osteoarthritis
Have a pacemaker, bone screws, or any other metal implants that would prohibit participation in an MRI scan or EWST
Non-English speaking individuals

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Cambridge?

Yes, this clinical trial (NCT06686680) has an active research site in Cambridge, MA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Knee Osteoarthristis Treatment Options in Cambridge, MA

If you're searching for knee osteoarthristis treatment options in Cambridge, MA, this clinical trial (NCT06686680) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Cambridge research site is actively enrolling participants for this clinical trial. You'll receive care from experienced knee osteoarthristis specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all knee osteoarthristis clinical trials near you to find additional studies recruiting in your area.

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