Pittsburgh, PANCT07308873Now EnrollingIRB Ready

Knee Osteoarthritis (OA) Clinical Trial in Pittsburgh, PA

Access cutting-edge knee osteoarthritis (oa) treatment through this clinical trial at a research site in Pittsburgh. Study-provided care at no cost to qualified participants.

Sponsored by University of Pittsburgh

Quick Self-Assessment

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Expert Care in Pittsburgh

Access knee osteoarthritis (oa) specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related knee osteoarthritis (oa) treatment provided free

Apply for This Pittsburgh Location

Check if you qualify for this knee osteoarthritis (oa) clinical trial in Pittsburgh, PA

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Pittsburgh

    Convenient for PA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Pittsburgh site if eligible
  4. 4Begin participation

About This Knee Osteoarthritis (OA) Study in Pittsburgh

The goal of this observational study is to look at inter-individual differences in knee osteoarthritis (OA) walking pain and performance. The main questions this study aims to answer are: Why do some people with knee osteoarthritis have more severe disabling pain than others, even though the degenerative changes in their knees are similar? What are the factors that contribute to walking pain in people with knee osteoarthritis? Participants will complete surveys, perform physical function tasks, get a knee X-ray and MRI, undergo non-invasive brain imaging, and undergo sensory testing.

Sponsor: University of Pittsburgh

Who Can Participate

Inclusion Criteria

Knee pain for greater than 6 months.
Moderate-to-severe knee pain (\>3/10) due to osteoarthritis, as defined by American College of Rheumatology and EULAR diagnostic criteria, on \>50% of days in the past month.
KL grade 2-4 indicating significant degenerative changes on knee X-ray.
45-80 years old

Exclusion Criteria

Inflammatory arthritis (e.g. rheumatoid arthritis).
More intense pain due to another chronic pain syndrome (e.g. fibromyalgia, hip osteoarthritis)
Significant pain or weakness in the lower extremities due to a neurological condition (e.g. lumbar radiculopathy, paresis due to stroke)
Acute pain that is more intense than knee osteoarthritis pain
Current routine use of more than 15 mg oral morphine equivalents per day (use of \<15 mg OME does not exclude the participant).
Recent new medication, exercise, behavioral, or complementary and integrative treatment started in the last month. Stable use of these treatments for greater than 1 month does not exclude the participant.
Recent intra-articular injection of steroid or other agent (greater than 1 month does not exclude the participant)
Recent knee radiofrequency ablation (greater than 3 months does not exclude the participant)
Recent knee arthroscopic surgery (greater than 3 months does not exclude the participant)
History of knee replacement or open knee surgery on the index knee, defined as the more painful knee on average over the last month.
Inability to walk or climb stairs without significant assistance (e.g. a one-person assist, use a wheel chair; however, the use of a cane does not exclude the participant).
Inability to participate in study procedures (e.g. cognitive impairment limiting ability to understand directions, inability to understand and read English)
Uncontrolled or unstable medical disorder preventing participation in study procedures
History of brain surgery
Tattoos on sensory testing sites
Breastfeeding
Inability to under knee MRI scan due to incompatible devices or foreign bodies.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Pittsburgh?

Yes, this clinical trial (NCT07308873) has an active research site in Pittsburgh, PA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Knee Osteoarthritis (OA) Treatment Options in Pittsburgh, PA

If you're searching for knee osteoarthritis (oa) treatment options in Pittsburgh, PA, this clinical trial (NCT07308873) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Pittsburgh research site is actively enrolling participants for this clinical trial. You'll receive care from experienced knee osteoarthritis (oa) specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all knee osteoarthritis (oa) clinical trials near you to find additional studies recruiting in your area.

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