Aurora, CONCT06940479Now EnrollingIRB Ready

Knee Osteoarthritis Clinical Trial in Aurora, CO

Access cutting-edge knee osteoarthritis treatment through this clinical trial at a research site in Aurora. Study-provided care at no cost to qualified participants.

Sponsored by University of Colorado, Denver

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Expert Care in Aurora

Access knee osteoarthritis specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related knee osteoarthritis treatment provided free

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Check if you qualify for this knee osteoarthritis clinical trial in Aurora, CO

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Why Participate?

  • No-Cost Study Care

  • Local to Aurora

    Convenient for CO residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Aurora site if eligible
  4. 4Begin participation

About This Knee Osteoarthritis Study in Aurora

The goal of this clinical trial is to learn if genicular artery embolization (GAE) can improve knee pain and decrease inflammation in adults with knee osteoarthritis. The main question it aims to answer is: \- Does the GAE procedure improve knee pain and decrease inflammation? Researchers will compare synovial fluid samples taken from the knee before and after the procedure. Participants will: * Have a contrast enhanced MRI before and after the procedure * Complete performance-based measures before and after the procedure * Complete questionnaires before and after the procedure

Sponsor: University of Colorado, Denver

Who Can Participate

Inclusion Criteria

Age ≥ 18 years
Planned to undergo genicular artery embolization to treat knee osteoarthritis.
Osteoarthritis on knee radiograph (Kellgren-Lawrence score 1-3) within the last 6 months
Persistent moderate to severe knee pain (visual analog scale \[VAS\] \>3) for at least 6 months
Pain refractory or intolerant to conservative therapies (e.g. analgesia, exercise, weight-loss, joint injections, physical therapy)
BMI \< 35 kg / m2
Stated willingness to comply with study procedures and availability for the duration of the study

Exclusion Criteria

Coagulation disturbances not normalized by medical treatment (INR \>1.8 and platelets \<50 x 10\^9/L)
Receiving medications for anticoagulation which cannot safely be held for the procedure (e.g ASA for 5 days, Lovenox for 24 hours, Eliquis for 4-6 days depending on creatinine clearance
Allergy to iodinated contrast agents not responsive to steroid premedication regimen
Active knee joint infection
Acute knee injury with surgical indication (MRI evidence of acute fracture or ligamentous injury of the knee)
Prior total or partial knee replacement in the subject knee
Intra-articular steroid injection within 2 months
Untreated lower extremity vascular arterial disease
Untreated venous insufficiency
Presence of medical condition with life expectancy less than 6 months
Patients who have undergone previous lower extremity embolization
Patients with renal insufficiency based on an estimated GFR\<45 ml/min who are not already on hemodialysis
Patients who are pregnant or intend to become pregnant within 6 months of the procedure
American Society of Anesthesiologists classification \> 3
Less than 3 mm of synovial fluid in the lateral suprapatellar recess on MRI or US

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Aurora?

Yes, this clinical trial (NCT06940479) has an active research site in Aurora, CO that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Knee Osteoarthritis Treatment Options in Aurora, CO

If you're searching for knee osteoarthritis treatment options in Aurora, CO, this clinical trial (NCT06940479) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Aurora research site is actively enrolling participants for this clinical trial. You'll receive care from experienced knee osteoarthritis specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all knee osteoarthritis clinical trials near you to find additional studies recruiting in your area.

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