Rochester, NYNCT04472702Now EnrollingIRB Ready

Knee Osteoarthritis Clinical Trial in Rochester, NY

Access cutting-edge knee osteoarthritis treatment through this clinical trial at a research site in Rochester. Study-provided care at no cost to qualified participants.

Sponsored by University of California, Davis

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Expert Care in Rochester

Access knee osteoarthritis specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related knee osteoarthritis treatment provided free

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Check if you qualify for this knee osteoarthritis clinical trial in Rochester, NY

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Rochester

    Convenient for NY residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Rochester site if eligible
  4. 4Begin participation

About This Knee Osteoarthritis Study in Rochester

Cooled radiofrequency ablation (cRFA) of the knee geniculate nerves is a promising treatment option for knee osteoarthritis, but has variable efficacy. Fluoroscopy is the typical guidance of choice, but uses bony landmarks to target these nerves which have variable positions around the knee. Alternatively, ultrasound allows for targeting based on visualization of bony landmarks, the nerves, and their accompanying vascular structures, and thus may offer greater accuracy. However, there are few studies which directly compare the clinical efficacy of these two guidance options. This study will compare these two options.

Sponsor: University of California, Davis

Who Can Participate

Inclusion Criteria

1\) patients of either gender with primary knee OA of one or both knees fulfilling the diagnostic criteria for knee OA by the American College of Rheumatology,
2\) Kellgren-Lawrence score of two to four,
3\) reported NPRS pain intensity of at least four on most or all days of the past week
4\) pain resistant to conventional treatments which may include but is not limited to medications (e.g. acetaminophen, oral or topical non-steroidal anti-inflammatory drugs, opioids), physical therapy, and intra-articular injections (e.g. corticosteroids, hyaluronic acid, platelet-rich-plasma) for at least 3 months. In the case of bilateral knee OA, the most symptomatic knee will be treated and studied.

Exclusion Criteria

1\) age \<35 years,
2\) non-English speaking patients,
3\) body mass index greater than 40,
4\) previous radiofrequency ablation procedure for the knee,
5\) active systemic or local infections at the site of needle/cRFA probe placement,
6\) previous knee joint replacement surgery,
7\) autoimmune or inflammatory cause of knee arthritis such as rheumatoid or psoriatic arthritis,
8\) non-ambulatory patients,
9\) patients who are unable to provide their own consent (e.g. dementia),
10\) unstable medical or psychiatric illness,
11\) patients with pacemakers, spinal cord stimulators, deep brain stimulators, or similar devices,
12\) patients seeking care as a part of workman's compensation or have litigation pending
13\) a negative response to diagnostic geniculate nerve lidocaine injections.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Rochester?

Yes, this clinical trial (NCT04472702) has an active research site in Rochester, NY that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Knee Osteoarthritis Treatment Options in Rochester, NY

If you're searching for knee osteoarthritis treatment options in Rochester, NY, this clinical trial (NCT04472702) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Rochester research site is actively enrolling participants for this clinical trial. You'll receive care from experienced knee osteoarthritis specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all knee osteoarthritis clinical trials near you to find additional studies recruiting in your area.

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