Skokie, ILNCT03491761Now EnrollingIRB Ready

Knee Osteoarthritis Clinical Trial in Skokie, IL

Access cutting-edge knee osteoarthritis treatment through this phase 2 clinical trial at a research site in Skokie. Study-provided care at no cost to qualified participants.

Sponsored by Endeavor Health

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Expert Care in Skokie

Access knee osteoarthritis specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related knee osteoarthritis treatment provided free

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Check if you qualify for this knee osteoarthritis clinical trial in Skokie, IL

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Skokie

    Convenient for IL residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Skokie site if eligible
  4. 4Begin participation

About This Knee Osteoarthritis Study in Skokie

This is a single-center, prospective, randomized, single-blind, comparator therapy, parallel group study for symptomatic patients diagnosed with knee osteoarthritis. The aim is to demonstrate superior efficacy of platelet-rich plasma (PRP) as compared to hyaluronic acid (HA) in treating knee osteoarthritis. This aim will be objectively measured by endpoint consisting of changes in cartilage thickness from baseline in the MRI. The Knee Injury and Osteoarthritis Outcome Score (KOOS) Questionnaire will be used to calculate The Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) total score. It will measure changes in pain and function from baseline. Approximately 100 subjects will be treated at NorthShore University HealthSystem (NorthShore) as part of this study. This study has the potential to improve outcomes in a very common chronic degenerative disease, osteoarthritis, which can have a significant effect on individuals' quality of life.

Sponsor: Endeavor Health

Who Can Participate

Inclusion Criteria

Ability to provide informed consent
Chronic pain (\>3 months)
Grade 2 -3 according to Kellgren- Lawrence (K-L) classification system (using bilateral anteroposterior radiograph image acquired while the patient is weight-bearing with both knees in full extension)
Minimum score of 40 out of possible 100 on the VAS (Visual Analog Scale) for pain
Age 18 to 75 years old
Physical exam and medical history
Complete Blood Count to include platelets and differential (CBC with Diff) within normal limits
C-Reactive Protein (CRP) within normal limits
Sed Rate (ESR) within normal limits
Survey of current medications

Exclusion Criteria

Presence of major axial deformity (\>5° valgus or varus deviation)
Surgery on target knee within 12 months prior to scheduled treatment
Autoimmune disorder
Active infections
Immuno-suppression (e.g., AIDS, etc.)
Anti-coagulant therapy
Use of NSAIDs 5 days prior to blood draw or up to 7 days after last PRP / HA treatment
Hemoglobin (Hg) \<12 g/dL
Platelet counts (PLT) \<150,000 /mm3
Previous infiltrative treatment within 3 weeks prior to scheduled treatment
Pregnancy/Breastfeeding
Hypersensitivity to HA
Inability to complete an MRI due to metal implants or claustrophobia
Active treatment for a malignancy
Active wound in the knee
Recent history of knee trauma
Vasovagal history
An injection of hyaluronic acid (HA) or platelet-rich plasma (PRP) to the affected knee within the last two years.
In the judgment of the investigator, the patient is unable to perform and/or complete all of the study visits or treatments required.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Skokie?

Yes, this clinical trial (NCT03491761) has an active research site in Skokie, IL that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Knee Osteoarthritis Treatment Options in Skokie, IL

If you're searching for knee osteoarthritis treatment options in Skokie, IL, this clinical trial (NCT03491761) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Skokie research site is actively enrolling participants for this phase 2 clinical trial. You'll receive care from experienced knee osteoarthritis specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all knee osteoarthritis clinical trials near you to find additional studies recruiting in your area.

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