Orange, CANCT04079179Now EnrollingIRB Ready

Langerhans Cell Histiocytosis Clinical Trial in Orange, CA

Access cutting-edge langerhans cell histiocytosis treatment through this clinical trial at a research site in Orange. Study-provided care at no cost to qualified participants.

Sponsored by Carl Allen

Quick Self-Assessment

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Expert Care in Orange

Access langerhans cell histiocytosis specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related langerhans cell histiocytosis treatment provided free

Apply for This Orange Location

Check if you qualify for this langerhans cell histiocytosis clinical trial in Orange, CA

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Orange

    Convenient for CA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Orange site if eligible
  4. 4Begin participation

About This Langerhans Cell Histiocytosis Study in Orange

This is a research study of a drug called cobimetinib in children and adults diagnosed with Langerhans cell histiocytosis (LCH), and other histiocytic disorders that has returned or does not respond to treatment. Cobimetinib blocks activation of a protein called Mitogen-activated protein kinase (MEK) that is part of incorrect growth signals in histiocytosis cells. Four different groups of patients will be enrolled.

Sponsor: Carl Allen

Who Can Participate

Inclusion Criteria

Age at study entry
For Group 1: Participant must be at least 6 months of age and less than 21 years of age at the time of enrollment
For Group 2: Participant may be at least 6 months of age at the time of enrollment
For Group 3: Participant must be at least 6 months of age and less than 21 years of age at the time of enrollment
For Group 4: Participant must be 21 years of age or older at the time of enrollment
Participant must be able to take an enteral dose and formulation of medication. Study medication is only available as an oral suspension or tablet which may be taken by mouth or other enteral route such as nasogastric or gastric tube.
Biopsy proven LCH -AND
Failure of at least front-line therapy for LCH with evaluable disease. -OR
Diagnosis of LCH-associated neurodegenerative disease with radiologic or clinical progression within the past 3 months. -OR
Biopsy proven JXG, ECD, RDD, histiocytic sarcoma, or other histiocytic lesion (newly diag

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Orange?

Yes, this clinical trial (NCT04079179) has an active research site in Orange, CA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Langerhans Cell Histiocytosis Treatment Options in Orange, CA

If you're searching for langerhans cell histiocytosis treatment options in Orange, CA, this clinical trial (NCT04079179) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Orange research site is actively enrolling participants for this clinical trial. You'll receive care from experienced langerhans cell histiocytosis specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

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Take the first step toward participating in this groundbreaking clinical trial

Secure · Expert Care · Orange, CA