Denver, CONCT07188558Now EnrollingIRB Ready

Large B-cell Lymphoma Clinical Trial in Denver, CO

Access cutting-edge large b-cell lymphoma treatment through this clinical trial at a research site in Denver. Study-provided care at no cost to qualified participants.

Sponsored by Lyell Immunopharma, Inc.

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Expert Care in Denver

Access large b-cell lymphoma specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related large b-cell lymphoma treatment provided free

Apply for This Denver Location

Check if you qualify for this large b-cell lymphoma clinical trial in Denver, CO

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Denver

    Convenient for CO residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Denver site if eligible
  4. 4Begin participation

About This Large B-cell Lymphoma Study in Denver

This Phase 3 study compares rondecabtagene autoleucel (ronde-cel), a dual-targeting CD19/CD20 CAR T-cell therapy, with investigator's choice of CD19 CAR T-cell therapy in patients with relapsed or refractory large B-cell lymphoma in the second-line setting.

Sponsor: Lyell Immunopharma, Inc.

Who Can Participate

Inclusion Criteria

CAR T cell naïve and eligible to receive a CD19 CART-cell therapy
Histologically confirmed large B-cell lymphoma, including the following types defined by (WHO 2022) or International Consensus Classification (2022)
Diffuse large B-cell lymphoma (DLBCL)
Transformations of indolent B-cell lymphomas (excluding Richter's transformation)
DLBCL/High-grade B-cell lymphoma (HGBCL) with MYC and BCL2 rearrangements
High-grade B-cell lymphoma (HGBCL) not otherwise specified (HGBCL NOS)
Primary mediastinal large B-cell lymphoma (PMBCL)
Grade 3B follicular lymphoma/large cell follicular lymphoma (FL3B)
Relapsed or refractory disease after anti-CD20 antibody and anthracycline-containing first-line chemoimmunotherapy
Measurable disease by presence of \[18F\]-fluorodeoxyglucose PET/CT positive lesion during Screening per Lugano Criteria
Eastern Cooperative Oncology Group (ECOG) performance status 0 or 1
Adequate hematological, renal, hepatic, pulmonary, and cardiac function Key

Exclusion Criteria

Patients ineligible to receive CD19 CAR T-cell therapy
Primary CNS lymphoma
Patients with primary cutaneous LBCL, human herpes virus-8 positive lymphoma, Burkitt lymphoma, T cell histiocyte-rich lymphoma, or transformation from chronic lymphocytic leukemia/small lymphocytic lymphoma (Richter's transformation)
Patients with prior history of malignancy, other than aggressive relapsed or refractory LBCL, unless the patient has been free of the disease for ≥ 2 years
Patients with uncontrolled systemic fungal, bacterial, viral, or other infection (including tuberculosis) despite appropriate antibiotics or other treatment
Active autoimmune disease requiring ongoing systemic immunosuppressive therapy. Note: Other protocol defined Inclusion/Exclusion criteria may apply

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Denver?

Yes, this clinical trial (NCT07188558) has an active research site in Denver, CO that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Large B-cell Lymphoma Treatment Options in Denver, CO

If you're searching for large b-cell lymphoma treatment options in Denver, CO, this clinical trial (NCT07188558) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Denver research site is actively enrolling participants for this clinical trial. You'll receive care from experienced large b-cell lymphoma specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all large b-cell lymphoma clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Denver, CO