Is NCT07125027 recruiting in Portland, OR?

Yes, NCT07125027 is currently recruiting participants at its Portland, OR location. This lumbosacral radiculopathy clinical trial is actively enrolling qualified participants.

How do I join the lumbosacral radiculopathy clinical trial in Portland?

To join this clinical trial in Portland, complete the eligibility form on this page. A study coordinator will contact you to discuss next steps and determine if you qualify.

Is participation in this Portland clinical trial free?

Yes, all study-related care is provided at no cost to qualified participants. Many studies also offer compensation for time and travel expenses.

Lumbosacral Radiculopathy Clinical Trial in Portland, OR

About This Lumbosacral Radiculopathy Study in Portland

The Move-MORE study is designed to evaluate a multicomponent mindfulness and movement program for patients with lumbosacral radiculopathy. The program brings together mindfulness training to help participants develop awareness of their body and manage pain-related stress, gentle movement practice to improve comfort with physical activity and support function, and motivational interviewing to strengthen motivation, confidence, and the ability to make healthy changes. The main objectives are to determine whether it is feasible for participants to use each component of the program when delivered online, to assess how acceptable and engaging each component is, and to evaluate the impact on pain, physical function, and daily activity levels. The study intervention will be conducted entirely remotely. Participants will complete online surveys, brief daily check-ins on their phone, and wear a small activity monitor on the hip to measure movement. They will also undergo quantitative sensory testing to evaluate pain sensitivity. At the end of the program, participants will share feedback about their experiences via qualitative interviews. The findings will help identify which parts of the program provide the greatest benefit, with the ultimate goal of developing a more targeted and effective digital program for people with this condition.

Sponsor: National University of Natural Medicine

Who Can Participate

Inclusion Criteria

● Adults age 18-65 years at the time of enrollment

Ability to stand for 10 minutes

Presence of lumbosacral radicular pain within the past week that extends below the knee (i.e., pain radiating from the low back into the leg in a nerve root distribution) with or without accompanying low back pain, of at least 12 weeks' duration, AND

Tampa Scale of Kinesiophobia score ≥ 23

At least one positive physical examination finding consistent with lumbosacral radiculopathy, including at least one of the following:

Positive straight leg raise test (eliciting radicular pain below the knee at ≤70 degrees of elevation);

Positive Valsalva maneuver (eliciting radiculcar pain below the knee);

Positive slump test;

Neurological deficit in a lumbar nerve root distribution, including at least one of the following:

Dermatomal sensory loss,

Myotomal weakness, or

Reduced or absent deep tendon reflexes (e.g., patellar or Achilles reflex) corresponding to the affected nerve root.

Daily access to the internet via cell phone, tablet, or computer

Willing to engage with Move-MORE 4-5 times per week on your own

Willing to attend a two-hour-long virtual Zoom meeting once per week for eight weeks

Willing to attend two in-person study visits and a follow-up visit

Willing to complete 18 questionnaires pertaining to your pain symptoms, quality of life, psychosocial experiences, and your experiences in the trial

Willing to wear an actigraphy device all day, every day, and while sleeping, for the duration of study participation and willing to keep it charged

Willing to respond to a daily online survey for the duration of study participation

Able to speak, read, and understand the English language

Able to provide written informed consent

Moderately motivated to participate as reported on a numeric rating scale (≥ 4/10)

Exclusion Criteria

● Participants will be excluded if they have clinical signs or symptoms of lumbosacral radiculopathy with progressive neurologic deficits (loss of motor or sensory function) or intolerable pain.

Participants with lumbosacral radiculopathy with progressive neurologic deficits will be referred for immediate medical attention, and are not eligible for participation in this study. ● Participants will be excluded if they have clinical signs or symptoms suggestive of cauda equina syndrome, including any of the following:

New-onset urinary retention or overflow incontinence not attributable to other known causes;

Fecal incontinence;

New onset of saddle anesthesia (loss of sensation in the buttocks, perineum, and inner thighs);

Severe or progressive bilateral lower extremity weakness;

Participants with suspected cauda equina syndrome will be referred for immediate medical attention, and are not eligible for participation in this study.

Presence of moderate to severe foot drop, defined as noticeable weakness in ankle dorsiflexion that interferes with walking or requires the use of an assistive device (e.g., ankle-foot orthosis). Participants with suspected or worsening foot drop will be referred for further evaluation and are not eligible for study participation.

Current use of a spinal cord stimulator

Have received epidural steroid injection in the prior 3 months

Have received a surgical intervention for low back pain or lumbosacral radiculopathy in the previous 6 months

Current active mindfulness meditation practice 1 time/week or more, and/or history of formal training in mindfulness/meditation practice

Concurrent diagnosis of cancer

Current unmanaged or uncontrolled mental illness known to cause psychosis: schizophrenia, schizotypal disorders, bipolar I disorder with psychosis, major depressive disorder with psychosis

Diagnosis of Borderline Personality Disorder or score \>6 on the McLean Screening Instrument for Borderline Personality Disorder

Initiation of or changes to an exercise regimen within 2 weeks prior to screening and/or enrollment

Major medical or surgical event requiring hospitalization (for any reason other than a minor scheduled medical procedure) within 3 months prior to screening; or, scheduled or will be scheduled to occur within the 20 weeks (i.e., five months) after enrollment

Currently participating in another interventional research study or participated in another interventional study within 2 weeks prior to screening

Any reason the Clinical Investigator or Principal Investigator believes confers increased risk to the potential participant, if they were to enroll in the study

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Portland?

Yes, this clinical trial (NCT07125027) has an active research site in Portland, OR that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Lumbosacral Radiculopathy Treatment Options in Portland, OR

If you're searching for lumbosacral radiculopathy treatment options in Portland, OR, this clinical trial (NCT07125027) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Portland research site is actively enrolling participants for this clinical trial. You'll receive care from experienced lumbosacral radiculopathy specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all lumbosacral radiculopathy clinical trials near you to find additional studies recruiting in your area.

Lumbosacral Radiculopathy Clinical Trial in Portland, OR

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