Is NCT02984761 recruiting in Indianapolis, IN?

Yes, NCT02984761 is currently recruiting participants at its Indianapolis, IN location. This lung neoplasm clinical trial is actively enrolling qualified participants.

How do I join the lung neoplasm clinical trial in Indianapolis?

To join this clinical trial in Indianapolis, complete the eligibility form on this page. A study coordinator will contact you to discuss next steps and determine if you qualify.

Is participation in this Indianapolis clinical trial free?

Yes, all study-related care is provided at no cost to qualified participants. Many studies also offer compensation for time and travel expenses.

Lung Neoplasm Clinical Trial in Indianapolis, IN

About This Lung Neoplasm Study in Indianapolis

Patients with stage I non-small cell lung cancer have been historically treated with surgery whenever they are fit for an operation. However, an alternative treatment known as stereotactic radiotherapy now appears to offer an equally effective alternative. Doctors believe both are good treatments and are therefore conducting this study to determine if one may be possibly better than the other.

Sponsor: VA Office of Research and Development

Who Can Participate

Inclusion Criteria

Age 18 or older

Any patient with a preliminary diagnosis of stage I Non-Small Cell Lung Cancer (NSCLC), whether pathologically proven by biopsy, or highly suspicious by radiographic imaging. \[Participants will ultimately need biopsy confirmation before enrolling\]

Primary tumor size less than or equal to 5 cm by CT (may include CT images from PET/CT)

Karnofsky performance status greater than or equal to 70

Participant has willingness and ability to provided informed consent for participation Inclusion Criteria for Randomization

Biopsy proven non-small cell lung cancer

Participant's case reviewed at multidisciplinary conference

Tumor size less than or equal to 5cm (measured on the most recent CT images available, and may include PET/CT images)

Tumor is equal to or greater than 1.0cm from the trachea, esophagus, brachial plexus, 1st bifurcation of the proximal bronchial tree, or spinal cord (measured on the most recent CT images available, and may include PET/CT images).

Mandatory FDG-PET/CT within 60 days of the randomization date (note: FDG-PET/CT may need to be repeated prior to treatment if outside of this requirement)

Mandatory pathological assessment of any lymph nodes \>10mm with a SUV \>2.5 seen on FDG- PET/CT

Mandatory biopsy of any additional concerning lesions seen on FDG-PET/CT, to make better determination that the patient is not harboring metastatic disease or a secondary primary malignancy.

Pre-operative FEV1 greater than or equal to 40% of predicted value and pre-operative DLCO greater than or equal to 40% of predicted value.

Formally evaluated and documented by a local thoracic surgeon to be medically fit to undergo a complete anatomic pulmonary resection (wedge resection not allowed)

Formally evaluated and documented by a local radiation oncologist to be eligible to receive protocol-defined stereotactic radiotherapy

Participant willingness to be randomized

Exclusion Criteria

Previously evaluated by a local thoracic surgeon and determined to be medically inoperable

Pathological confirmation of nodal or distant metastasis

Prior history of lung cancer, not including current lesion

Prior history of thoracic surgery or lung or esophageal cancer. \[prior cardiac surgery acceptable\]

Prior history of radiotherapy to the thorax

Prior history of invasive state I-III malignancy treated with surgery, radiation therapy, chemotherapy, immunotherapy, or targeted therapy in the past 2 years, excluding prostate cancer, low-risk papillary thyroid cancer (less than or equal to 1 cm), follicular lymphoma, or chronic lymphocytic leukemia.

Prior history of IV malignancy, excluding follicular lymphoma, chronic lymphocytic leukemia, or hormone sensitive prostate cancer confined to the pelvis.

Ever diagnosed with stage IV metastatic cancer of any type

History of scleroderma

Positive Pregnancy test (for women \<61 years of age or without prior hysterectomy) Exclusion Criteria for Randomization

Pathological confirmation of nodal or metastatic disease

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Indianapolis?

Yes, this clinical trial (NCT02984761) has an active research site in Indianapolis, IN that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Lung Neoplasm Treatment Options in Indianapolis, IN

If you're searching for lung neoplasm treatment options in Indianapolis, IN, this clinical trial (NCT02984761) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Indianapolis research site is actively enrolling participants for this clinical trial. You'll receive care from experienced lung neoplasm specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all lung neoplasm clinical trials near you to find additional studies recruiting in your area.

Lung Neoplasm Clinical Trial in Indianapolis, IN

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